Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.43 |
| ▸ | JAK1 | P23458 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 5/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18419034 | 0.88 | JAK1 (0.48) | GPR119JAK1CYP2C9JAK2NAMPT | |
| SCHEMBL10226760 | 0.85 | GPR119 (0.45) | GPR119JAK1CYP2C9JAK2JAK3 | |
| SCHEMBL29838827 | 0.85 | JAK1 (0.58) | GPR119JAK1JAK2JAK3 | |
| SCHEMBL24491120 | 0.83 | JAK1 (0.46) | GPR119JAK1CYP2C9JAK2JAK3 | |
| SCHEMBL29622271 | 0.83 | GPR119 (0.39) | GPR119JAK1CYP2C9JAK2JAK3 | |
| SCHEMBL17500887 | 0.82 | JAK1 (0.49) | GPR119JAK1JAK2JAK3 | |
| SCHEMBL17500886 | 0.82 | JAK1 (0.49) | GPR119JAK1JAK2JAK3 | |
| SCHEMBL19757372 | 0.82 | GPR119 (0.47) | GPR119JAK1JAK2JAK3 | |
| SCHEMBL29711973 | 0.82 | JAK2 (0.46) | GPR119JAK1JAK2JAK3 | |
| SCHEMBL2732774 | 0.81 | GPR119 (0.42) | GPR119JAK1CYP2C9JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591321-A | Aza-and-cyclic compounds, method for the production thereof and use thereof | 广州费米子科技有限责任公司 | 2022-06-07 | — | — | CN | disclosed |