Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.40 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398554 | 1.00 | DDX3X (0.42) | DDX3XNAMPTNPSR1MAPK10KCNQ3 | |
| SCHEMBL402719 | 0.90 | KCNQ3 (0.43) | DDX3XNAMPTNPSR1MAPK10KCNQ3 | |
| SCHEMBL29714053 | 0.85 | TAAR1 (0.54) | NAMPTNPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL1446211 | 0.83 | HRH3 (0.45) | DDX3XNPSR1MAPK10KCNQ3KCNQ2 | |
| SCHEMBL402720 | 0.82 | NPSR1 (0.40) | NAMPTNPSR1MAPK10KCNQ3KCNQ2 | |
| SCHEMBL398555 | 0.79 | NPSR1 (0.41) | DDX3XNAMPTNPSR1MAPK10KCNQ3 | |
| SCHEMBL399932 | 0.79 | CYP1A2 (0.41) | DDX3XCYP1A2KMT2A | |
| SCHEMBL3211164 | 0.79 | NPSR1 (0.47) | DDX3XNAMPTNPSR1MAPK10KCNQ3 | |
| SCHEMBL1446415 | 0.79 | HRH3 (0.43) | DDX3XNPSR1MAPK10KCNQ3KCNQ2 | |
| SCHEMBL3211160 | 0.78 | NPSR1 (0.46) | DDX3XNPSR1MAPK10KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12264133-B2 | Compounds, compositions and methods | CYTOKINETICS, INCORPORATED (US) | 2025-04-01 | — | — | US | disclosed |
| US-20220185779-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INCORPORATED | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185779-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | TNNI3, TNNC1, TNNT2 | DDX3X 1478/4885NAMPT 3383/4885NPSR1 4780/4885 |
| US-12264133-B2 | Compounds, compositions and methods | TNNI3, TNNC1, TNNT2 | DDX3X 1478/4885NAMPT 3383/4885NPSR1 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.