Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20014854 | 0.73 | MTNR1A (0.61) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL10317785 | 0.72 | MEN1 (0.50) | GPR88CTSKCTSSMEN1GAA | |
| SCHEMBL10317783 | 0.72 | MEN1 (0.50) | GPR88CTSKCTSSMEN1GAA | |
| SCHEMBL10318441 | 0.72 | MEN1 (0.50) | GPR88CTSKCTSSMEN1GAA | |
| SCHEMBL27461037 | 0.71 | MEN1 (0.49) | GPR88CKS1BSKP1SKP2CTSK | |
| SCHEMBL16084764 | 0.71 | RIPK1 (0.53) | GPR88CTSKCTSSMEN1GAA | |
| SCHEMBL1521024 | 0.71 | RIPK1 (0.53) | GPR88CTSKCTSSMEN1GAA | |
| SCHEMBL10323702 | 0.70 | MEN1 (0.58) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL27334285 | 0.70 | CKS1B (0.39) | CKS1BSKP1SKP2MEN1GAA | |
| SCHEMBL3047789 | 0.70 | MEN1 (0.45) | GPR88CTSKCTSSMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943945-B | Suvorexant intermediate and preparation method thereof | 上海应用技术大学 | 2022-07-12 | — | — | CN | disclosed |