SCHEMBL29720334

SCHEMBL29720334

CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)C(C)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTSD P07339 2/20 0.53
OPRD1 P41143 7/20 0.50
OPRM1 P35372 4/20 0.50
OPRK1 P41145 1/20 0.50
CTSC P53634 2/20 0.49
MME P08473 2/20 0.49
ACE P12821 1/20 0.49
CPA1 P15085 1/20 0.49
ACE2 Q9BYF1 1/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
ANPEP P15144 1/20 0.48
ECE1 P42892 1/20 0.48
ALPI P09923 1/20 0.48
PKM P14618 1/20 0.48
PTGS1 P23219 1/20 0.48
XIAP P98170 1/20 0.48
SLC7A5 Q01650 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051265 1.00 CTSD (0.53) CTSDOPRD1OPRM1OPRK1CTSC
SCHEMBL3052108 0.95 CTSD (0.57) CTSDCTSCMMEACECPA1
SCHEMBL3052110 0.95 CTSD (0.57) CTSDCTSCMMEACECPA1
SCHEMBL30050842 0.92 CTSD (0.60) CTSDCTSCMMEACECPA1
SCHEMBL31462339 0.92 CTSD (0.60) CTSDCTSCMMEACECPA1
SCHEMBL30714767 0.90 OPRD1 (0.53) OPRD1OPRM1OPRK1MMEACE
SCHEMBL3202596 0.90 CTSD (0.64) CTSDCTSCMMEACECPA1
SCHEMBL30052367 0.90 CTSD (0.58) CTSDCTSCMMEACECPA1
SCHEMBL30050940 0.90 CTSD (0.64) CTSDCTSCMMEACECPA1
SCHEMBL30051904 0.89 MME (0.57) CTSDOPRD1OPRM1OPRK1MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11382956-B2 Amylin analogues ZEALAND PHARMA A/S (DK) 2022-07-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11382956-B2 Amylin analogues IAPP, GLP1R, AMY2A CTSD 830/4885OPRD1 2996/4885OPRM1 2772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.