Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176363 | 1.00 | DRD2 (0.37) | DRD2DRD4TNKS2ESR2PTPRC | |
| SCHEMBL9453911 | 0.84 | DRD2 (0.41) | DRD2DRD4ESR2TYRMAOA | |
| SCHEMBL30688503 | 0.76 | TNKS2 (0.36) | TNKS2 | |
| SCHEMBL7111337 | 0.76 | TNKS2 (0.36) | TNKS2 | |
| SCHEMBL15161193 | 0.76 | GAA (0.38) | TNKS2 | |
| SCHEMBL762345 | 0.72 | ALDH1A1 (0.34) | TNKS2 | |
| SCHEMBL22278266 | 0.72 | TNKS2 (0.34) | TNKS2 | |
| SCHEMBL6648586 | 0.72 | TNKS2 (0.39) | TNKS2 | |
| SCHEMBL10242603 | 0.72 | TNKS2 (0.41) | TNKS2 | |
| SCHEMBL7472650 | 0.71 | DRD2 (0.36) | DRD2DRD4ESR2TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112745262-B | Preparation method of brexpiprazole intermediate 7-hydroxy-1H-quinoline-2-ketone | 江苏恩华药业股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-120865178-A | Eperide Process for preparing azoles | 济宁晟泰药业有限公司 | 2025-10-31 | — | — | CN | disclosed |
| CN-112858524-B | Detection method and application of brexpiprazole related substance | 丽珠集团新北江制药股份有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-112745262-B | Preparation method of brexpiprazole intermediate 7-hydroxy-1H-quinoline-2-ketone | 江苏恩华药业股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-112745262-B | Preparation method of brexpiprazole intermediate 7-hydroxy-1H-quinoline-2-ketone | 江苏恩华药业股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-112745262-B | Preparation method of brexpiprazole intermediate 7-hydroxy-1H-quinoline-2-ketone | 江苏恩华药业股份有限公司 | 2022-07-12 | — | — | CN | disclosed |