SCHEMBL29720476

SCHEMBL29720476

CC(C)(C)c1cc(Cl)cc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.40
ALDH1A1 P00352 3/20 0.37
HIF1A Q16665 1/20 0.37
CYP1B1 Q16678 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CYP1A2 P05177 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
KIF11 P52732 1/20 0.34
GPR84 Q9NQS5 2/20 0.33
HPGD P15428 1/20 0.33
TRPM4 Q8TD43 1/20 0.33
ACP3 P15309 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12401757 1.00 CYP2A6 (0.40) CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL28771103 0.80 CYP1A2 (0.41) CYP2A6ALDH1A1CYP1B1CYP1A2KIF11
SCHEMBL26522360 0.78 CYP2A6 (0.43) CYP2A6ALDH1A1CYP1A2TSHRTDP1
Bromide SCHEMBL21461363 0.78 ALDH1A1 (0.35) CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL18053304 0.78 PGR (0.47) CYP1B1CYP1A2ESR2
SCHEMBL24712674 0.78 CYP1A2 (0.57) CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL26579482 0.78 CYP1A2 (0.39) CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL15853141 0.78 CYP1A2 (0.41) CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL17030753 0.76 ALDH1A1 (0.40) CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL2454488 0.76 CYP2A6 (0.40) CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756598-A Preparation method of 1- (tertiary butyl) -3-chloronaphthalene 中钢集团南京新材料研究院有限公司 2024-03-26 CN claimed
CN-114736099-B Preparation method of 1- (tertiary butyl) -3-chloronaphthalene 江苏南大光电材料股份有限公司 2023-06-06 CN claimed
CN-114736099-A Preparation method of 1- (tert-butyl) -3-chloronaphthalene 江苏南大光电材料股份有限公司 2022-07-12 CN claimed
CN-118955572-A Organic electroluminescent material and device 环球展览公司 2024-11-15 CN disclosed
CN-118955570-A Organic electroluminescent material and device 环球展览公司 2024-11-15 CN disclosed
CN-118955571-A Organic electroluminescent material and device 环球展览公司 2024-11-15 CN disclosed
CN-115974903-B Preparation method of 2- (4- (tert-butyl) naphthalene-2-yl) -4, 5-tetramethyl-1, 3, 2-dioxaborane 中钢集团南京新材料研究院有限公司 2024-10-29 CN disclosed
CN-107892702-B Organic electroluminescent material and device 环球展览公司 2024-08-20 CN disclosed
CN-117756598-A Preparation method of 1- (tertiary butyl) -3-chloronaphthalene 中钢集团南京新材料研究院有限公司 2024-03-26 CN disclosed
CN-117756598-A Preparation method of 1- (tertiary butyl) -3-chloronaphthalene 中钢集团南京新材料研究院有限公司 2024-03-26 CN disclosed
CN-117756598-A Preparation method of 1- (tertiary butyl) -3-chloronaphthalene 中钢集团南京新材料研究院有限公司 2024-03-26 CN disclosed
WO-2023221165-A1 METHOD FOR PREPARING 1-(TERT-BUTYL)-3-CHLORONAPHTHALENE 江苏南大光电材料股份有限公司 2023-11-23 WO disclosed
CN-116969984-A Preparation method of 2- (4- (tert-butyl) naphthalene-2-yl) -4, 5-tetramethyl-1, 3, 2-dioxaborane 郑州药领医药科技有限公司 2023-10-31 CN disclosed
CN-114736099-B Preparation method of 1- (tertiary butyl) -3-chloronaphthalene 江苏南大光电材料股份有限公司 2023-06-06 CN disclosed
CN-114736099-B Preparation method of 1- (tertiary butyl) -3-chloronaphthalene 江苏南大光电材料股份有限公司 2023-06-06 CN disclosed
CN-114736099-B Preparation method of 1- (tertiary butyl) -3-chloronaphthalene 江苏南大光电材料股份有限公司 2023-06-06 CN disclosed
CN-115974903-A Preparation method of 2- (4- (tert-butyl) naphthalene-2-yl) -4, 5-tetramethyl-1, 3, 2-dioxaborane 中钢集团南京新材料研究院有限公司 2023-04-18 CN disclosed
CN-114736099-A Preparation method of 1- (tert-butyl) -3-chloronaphthalene 江苏南大光电材料股份有限公司 2022-07-12 CN disclosed
CN-114736099-A Preparation method of 1- (tert-butyl) -3-chloronaphthalene 江苏南大光电材料股份有限公司 2022-07-12 CN disclosed
CN-114736099-A Preparation method of 1- (tert-butyl) -3-chloronaphthalene 江苏南大光电材料股份有限公司 2022-07-12 CN disclosed