Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29720476 | 1.00 | CYP2A6 (0.40) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL28771103 | 0.80 | CYP1A2 (0.41) | CYP2A6ALDH1A1CYP1B1CYP1A2KIF11 | |
| SCHEMBL26522360 | 0.78 | CYP2A6 (0.43) | CYP2A6ALDH1A1CYP1A2TSHRTDP1 | |
| Bromide SCHEMBL21461363 | 0.78 | ALDH1A1 (0.35) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL18053304 | 0.78 | PGR (0.47) | CYP1B1CYP1A2ESR2 | |
| SCHEMBL24712674 | 0.78 | CYP1A2 (0.57) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL26579482 | 0.78 | CYP1A2 (0.39) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL15853141 | 0.78 | CYP1A2 (0.41) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL17030753 | 0.76 | ALDH1A1 (0.40) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL2454488 | 0.76 | CYP2A6 (0.40) | CYP2A6ALDH1A1HIF1ACYP1B1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756598-A | Preparation method of 1- (tertiary butyl) -3-chloronaphthalene | 中钢集团南京新材料研究院有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-114736099-B | Preparation method of 1- (tertiary butyl) -3-chloronaphthalene | 江苏南大光电材料股份有限公司 | 2023-06-06 | — | — | CN | claimed |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | OMEROS CORPORATION (US) | 2024-07-09 | — | — | US | disclosed |
| CN-117756598-A | Preparation method of 1- (tertiary butyl) -3-chloronaphthalene | 中钢集团南京新材料研究院有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117756598-A | Preparation method of 1- (tertiary butyl) -3-chloronaphthalene | 中钢集团南京新材料研究院有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117756598-A | Preparation method of 1- (tertiary butyl) -3-chloronaphthalene | 中钢集团南京新材料研究院有限公司 | 2024-03-26 | — | — | CN | disclosed |
| WO-2023221165-A1 | METHOD FOR PREPARING 1-(TERT-BUTYL)-3-CHLORONAPHTHALENE | 江苏南大光电材料股份有限公司 | 2023-11-23 | — | — | WO | disclosed |
| WO-2023221165-A1 | METHOD FOR PREPARING 1-(TERT-BUTYL)-3-CHLORONAPHTHALENE | 江苏南大光电材料股份有限公司 | 2023-11-23 | — | — | WO | disclosed |
| US-20230322788-A1 | IMIDAZOTRIAZINE AND PYRROLOPYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2023-10-12 | — | — | US | disclosed |
| EP-3301088-B1 | CONDENSED PYRIDINES AS ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORP (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-114736099-B | Preparation method of 1- (tertiary butyl) -3-chloronaphthalene | 江苏南大光电材料股份有限公司 | 2023-06-06 | — | — | CN | disclosed |
| US-20180097179-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2018-04-05 | — | — | US | disclosed |
| US-20180097179-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2018-04-05 | — | — | US | disclosed |
| US-20180097187-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2018-04-05 | — | — | US | disclosed |
| EP-3301088-A1 | CONDENSED PYRIDINES AS ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2018-04-04 | — | — | EP | disclosed |
| US-8735398-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130085147-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-04 | — | — | US | disclosed |
| US-8372873-B2 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-02-12 | — | — | US | disclosed |
| US-20110182856-A1 | INHIBITORS OF SERINE PROTEASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-07-28 | — | — | US | disclosed |
| US-7964624-B1 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180097187-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OCIAD2, OSBP | CYP2A6 3152/4885ALDH1A1 1035/4885HIF1A 4823/4885 |
| US-20130085147-A1 | Hepatitis C Virus Inhibitors | HAVCR2, MAVS, GTF3C1 | CYP2A6 2321/4885ALDH1A1 3778/4885HIF1A 4147/4885 |
| US-20230322788-A1 | IMIDAZOTRIAZINE AND PYRROLOPYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS | KRAS, NRAS, HRAS | CYP2A6 4169/4885ALDH1A1 3193/4885HIF1A 3403/4885 |
| US-20180097179-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OCIAD2, OSBP | CYP2A6 3357/4885ALDH1A1 994/4885HIF1A 4736/4885 |
| US-20110182856-A1 | INHIBITORS OF SERINE PROTEASES | PRSS1, SPINT2, PRSS2 | CYP2A6 895/4885ALDH1A1 1255/4885HIF1A 3923/4885 |
| US-12030853-B2 | MASP-2 inhibitors and methods of use | MASP2, METAP2, SPINT2 | CYP2A6 4656/4885ALDH1A1 4709/4885HIF1A 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.