Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 4/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30612348 | 0.89 | PKM (0.46) | LMNAL3MBTL1HPGDLRRK2TLR7 | |
| SCHEMBL23123137 | 0.86 | BCL9 (0.39) | L3MBTL1HPGDLRRK2HSD11B1BCL9 | |
| SCHEMBL30019792 | 0.82 | RBP4 (0.41) | LMNAL3MBTL1HPGDCDK1CDK2 | |
| SCHEMBL30267336 | 0.81 | LRRK2 (0.41) | LMNAL3MBTL1HPGDLRRK2KMT2A | |
| SCHEMBL31696984 | 0.80 | KDM1A (0.40) | L3MBTL1HPGDLRRK2TLR7TLR8 | |
| SCHEMBL30816887 | 0.79 | FFAR4 (0.39) | LMNAL3MBTL1HPGDCDK1CDK2 | |
| SCHEMBL21409448 | 0.79 | HSD11B1 (0.42) | LMNACDK1CDK2CASP3GSK3B | |
| SCHEMBL29384321 | 0.79 | KMT2A (0.42) | LMNAL3MBTL1HPGDTLR7TLR8 | |
| SCHEMBL23121698 | 0.79 | HSD11B1 (0.44) | LMNAL3MBTL1CDK1CDK2CASP3 | |
| Hydrochloric Acid SCHEMBL23122710 | 0.78 | HSD11B1 (0.43) | LMNACDK1CDK2CASP3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114641473-A | BRD9 bifunctional degradation agent and use method thereof | 诺华股份有限公司 | 2022-06-17 | — | — | CN | disclosed |