Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BID | P55957 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23148045 | 1.00 | PTGDR2 (0.42) | PTGDR2CCR2AGTR1NOD2NOD1 | |
| SCHEMBL23147852 | 0.89 | PTGDR2 (0.43) | PTGDR2CCR2AGTR1NOD2NOD1 | |
| SCHEMBL28391967 | 0.78 | ABL1 (0.40) | PTGDR2CCR2AGTR1NOD2NOD1 | |
| SCHEMBL23147514 | 0.76 | PTGDR2 (0.40) | PTGDR2CCR2AGTR1NOD2NOD1 | |
| SCHEMBL29722021 | 0.74 | L3MBTL1 (0.43) | NOD1HTT | |
| SCHEMBL23147979 | 0.74 | L3MBTL1 (0.43) | NOD1HTT | |
| SCHEMBL29721782 | 0.74 | PTGDR2 (0.42) | PTGDR2CCR2AGTR1NOD2NOD1 | |
| SCHEMBL23147614 | 0.74 | PTGDR2 (0.42) | PTGDR2CCR2AGTR1NOD2NOD1 | |
| SCHEMBL23147553 | 0.73 | AGTR1 (0.40) | PTGDR2CCR2AGTR1NOD2NOD1 | |
| SCHEMBL23147907 | 0.73 | PTGDR2 (0.41) | PTGDR2CCR2AGTR1NOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4034108-A1 | AZAINDOLE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | The Global Alliance for TB Drug Development, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |