Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17492862 | 0.85 | PSEN1 (0.39) | ABL1BCRPSEN1PSEN2APH1B | |
| SCHEMBL28234746 | 0.79 | HTT (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL23148045 | 0.78 | PTGDR2 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29722020 | 0.78 | PTGDR2 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28504285 | 0.76 | CA1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28500443 | 0.76 | AGTR1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28496364 | 0.75 | NOD2 (0.39) | ABL1BCRPSEN1PSEN2APH1B | |
| SCHEMBL2128761 | 0.74 | ABL1 (0.45) | ABL1BCRKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL31279720 | 0.73 | ALDH1A1 (0.37) | ABL1BCRPSEN1PSEN2APH1B | |
| SCHEMBL19252020 | 0.73 | ALDH1A1 (0.37) | ABL1BCRPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110964012-B | Fused heterocyclic biaryl benzyl alcohol compound, preparation method and application | 上海凌达生物医药有限公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-110964012-A | Fused heterocyclic biaryl benzyl alcohol compound, preparation method and application | 如东凌达生物医药科技有限公司 | 2020-04-07 | — | — | CN | disclosed |