Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627498 | 1.00 | HSD17B10 (0.47) | HSD17B10ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28631099 | 0.86 | CACNA2D1 (0.49) | ALDH1A1HIF1AUSP2HTT | |
| Hydrochloric Acid SCHEMBL30669828 | 0.85 | CACNA2D1 (0.48) | ALDH1A1HIF1AMAPTALOX15MAPK1 | |
| SCHEMBL17678330 | 0.83 | POLB (0.49) | ALDH1A1SMN1; SMN2HIF1AMAPTALOX15 | |
| SCHEMBL29724008 | 0.81 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL2044138 | 0.79 | HDAC6 (0.46) | HSD17B10ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3820085 | 0.78 | USP2 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL29724012 | 0.78 | AURKA (0.48) | HSD17B10ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9953779 | 0.76 | ALOX15 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5741522 | 0.76 | USP2 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461661-B | 6- (pyridin-3-yl) quinazoline-4 (3H) -ketone derivative and preparation and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-28 | — | — | CN | disclosed |
| CN-110655505-B | 6- (2-amino-1H-benzo [ d ] imidazol-6-yl) quinazolin-4 (3H) -ones | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2022-06-21 | — | — | CN | disclosed |