Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9960599 | 0.94 | MAPK1 (0.49) | ALOX15MAPK1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14247511 | 0.83 | ALOX15 (0.53) | ALOX15MAPK1ALDH1A1TSHRKMT2A | |
| SCHEMBL31241091 | 0.80 | CACNA2D1 (0.47) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL10288755 | 0.79 | POLR1A (0.41) | ALOX15MAPK1ALDH1A1HTTCACNA2D1 | |
| SCHEMBL14247207 | 0.77 | ALOX15 (0.47) | ALOX15MAPK1GAAALDH1A1TSHR | |
| SCHEMBL10289136 | 0.77 | CACNA2D1 (0.51) | MEN1KMT2AHTTMAPTCACNA2D1 | |
| SCHEMBL9953325 | 0.77 | HSD17B10 (0.49) | ALOX15ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10288782 | 0.77 | CACNA2D1 (0.39) | ALDH1A1MEN1KMT2AHTTKDM4E | |
| SCHEMBL29723966 | 0.76 | HSD17B10 (0.47) | ALOX15MAPK1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL28627498 | 0.76 | HSD17B10 (0.47) | ALOX15MAPK1GAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |