SCHEMBL2973228

SCHEMBL2973228

Cc1cc(C)c(C(=O)P(=O)(c2cc(C)ccc2C)c2cc(C)ccc2C)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
HPGD P15428 2/20 0.37
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GAA P10253 1/20 0.35
TAS1R3 Q7RTX0 3/20 0.35
TAS1R1 Q7RTX1 3/20 0.35
TAS1R2 Q8TE23 3/20 0.35
NPSR1 Q6W5P4 1/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
RAPGEF4 Q8WZA2 1/20 0.33
HTT P42858 1/20 0.33
CISD2 Q8N5K1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29372058 0.86 GAA (0.39) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL58579 0.86 GAA (0.39) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL5145424 0.83 KMT2A (0.37) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL11062242 0.81 GAA (0.40) KMT2AGAATAS1R3TAS1R1TAS1R2
SCHEMBL5145413 0.79 LMNA (0.45) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL11058064 0.79 CA12 (0.44) KMT2AMEN1HPGDGAATAS1R3
SCHEMBL11059161 0.77 RAPGEF4 (0.37) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL28510079 0.76 HTT (0.38) KMT2AMEN1HPGDLMNASMN1; SMN2
SCHEMBL6469382 0.75 S1PR4 (0.43) KMT2AMEN1SMN1; SMN2GAA
SCHEMBL29759580 0.74 LMNA (0.36) KMT2AMEN1HPGDLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7776109-B2 Method for producing acylphosphine oxide solids BASF AKTIENGESELLSCHAFT (DE) 2010-08-17 US disclosed
US-20070167653-A1 Method for producing acylphosphine oxide solids BASF AKIENGESELLSCHAFT (DE) 2007-07-19 US disclosed
US-4447520-A PHOTOINITIATOR FOR PHOTOPOLYMERIZATION BASF AKTIENGESELLSCHAFT (DE) 1984-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070167653-A1 Method for producing acylphosphine oxide solids AGPAT5, PHOSPHO1, AGPS KMT2A 2152/4885MEN1 1381/4885HPGD 3436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.