SCHEMBL6469382

SCHEMBL6469382

Cc1ccc(C)c(P(=O)(C(=O)c2c(C)cccc2C)C(=O)c2c(C)cccc2C)c1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 9/20 0.43
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
S1PR2 O95136 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KCNK3 O14649 2/20 0.36
KCNK9 Q9NPC2 2/20 0.36
KCNH2 Q12809 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29372058 0.88 GAA (0.39) S1PR4KDM4EMAPTGAASMN1; SMN2
SCHEMBL58579 0.88 GAA (0.39) S1PR4KDM4EMAPTGAASMN1; SMN2
SCHEMBL29365063 0.86 GAA (0.40) S1PR4KDM4EMAPTHDAC8HDAC6
SCHEMBL58444 0.86 GAA (0.40) S1PR4KDM4EMAPTHDAC8HDAC6
SCHEMBL711411 0.83 NPC1 (0.46) MAPTGAAMEN1KMT2AKCNK3
SCHEMBL29374425 0.82 TAS1R3 (0.42) GAASMN1; SMN2MEN1KMT2A
SCHEMBL57625 0.82 TAS1R3 (0.42) GAASMN1; SMN2MEN1KMT2A
SCHEMBL29412973 0.78 KMT2A (0.37) KDM4EGAASMN1; SMN2MEN1KMT2A
SCHEMBL442498 0.78 KMT2A (0.37) KDM4EGAASMN1; SMN2MEN1KMT2A
SCHEMBL7635001 0.77 LMNA (0.45) S1PR4MAPTHDAC6GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050096406-A1 Reactive diluents and alkyd resin coating compositions PRETOT ROGER (CH) 2005-05-05 US disclosed
US-5534559-A UNSATURATED POLYESTERS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed