Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24553685 | 1.00 | CSNK2A1 (0.34) | CSNK2A1CYP1A2ARGAAHTT | |
| SCHEMBL11583058 | 0.84 | GAA (0.34) | CSNK2A1ARGAAHTT | |
| SCHEMBL10284441 | 0.78 | GAA (0.54) | CYP1A2GAAHTTKDM4EGRIN2D | |
| SCHEMBL11585640 | 0.77 | MAPT (0.39) | CYP1A2KDM4EALDH1A1PSMB8EGFR | |
| SCHEMBL15844358 | 0.75 | RAD52 (0.43) | CYP1A2GAAHTTKDM4EGRIN2D | |
| SCHEMBL11339364 | 0.74 | TDP1 (0.47) | GAAHTTKDM4EALDH1A1PSMB8 | |
| SCHEMBL6311477 | 0.73 | GAA (0.62) | CSNK2A1ARGAAHTTGRIN2D | |
| SCHEMBL19399634 | 0.73 | PRKAG1 (0.42) | GAAKDM4EGRIN2DGRIN3BALDH1A1 | |
| SCHEMBL7045022 | 0.71 | CYP1A2 (0.40) | CYP1A2ARGAAHTTKDM4E | |
| SCHEMBL11749723 | 0.71 | TSHR (0.36) | CYP1A2GAAKDM4EGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634491-B | Polycyclic compound for inhibiting RNA helicase DHX33 | 成都开悦生命科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114634491-A | Polycyclic compound for inhibiting RNA helicase DHX33 | 成都开悦生命科技有限公司 | 2022-06-17 | — | — | CN | disclosed |