SCHEMBL18619403

SCHEMBL18619403

O=C(c1ccc(O)c(O)c1)N1CCC(c2noc3ccc(F)cc23)CC1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
LMNA P02545 1/20 0.54
HTR1A P08908 1/20 0.54
HTR1F P30939 1/20 0.54
SCD O00767 1/20 0.52
HTR2A P28223 2/20 0.50
DRD3 P35462 1/20 0.50
ALDH1A1 P00352 1/20 0.50
GAA P10253 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
HTR7 P34969 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18619477 0.84 HTT (0.54) HTTSMN1; SMN2LMNAHTR1AHTR1F
SCHEMBL23351594 0.83 ACHE (0.55)
SCHEMBL10637192 0.82 HTT (0.61) HTTSMN1; SMN2LMNAHTR1AHTR1F
SCHEMBL22491514 0.80 MGLL (0.56) HTR1AHTR1FHTR2ADRD3
SCHEMBL29734583 0.80 MGLL (0.56) HTR1AHTR1FHTR2ADRD3
SCHEMBL18763046 0.79 HTT (0.55) HTTSMN1; SMN2LMNAHTR1AHTR1F
SCHEMBL21143169 0.78 HTT (0.55) HTTSMN1; SMN2LMNAHTR1AHTR1F
SCHEMBL29688909 0.76 HTR2A (0.46) HTTSMN1; SMN2LMNAHTR1AHTR1F
SCHEMBL20135089 0.76 HTR2A (0.46) HTTSMN1; SMN2LMNAHTR1AHTR1F
SCHEMBL20135091 0.76 HTR2A (0.46) HTTSMN1; SMN2LMNAHTR1AHTR1F

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3345910-B1 COMPOUND HAVING EFFECT OF INHIBITING PLATELET AGGREGATION AND SALT THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING THROMBOTIC DISEASES, CONTAINING SAME SHIN POONG PHARMACEUTICAL CO LTD (KR) 2023-11-01 EP claimed
US-10730886-B2 Compound having effect of inhibiting platelet aggregation and salt thereof, and composition for preventing or treating thrombotic diseases, containing same SHIN POONG PHARMACEUTICAL CO., LTD. (KR) 2020-08-04 US claimed
US-20180251472-A1 Compound Having Effect Of Inhibiting Platelet Aggregation And Salt Thereof, And Composition For Preventing Or Treating Thrombotic Diseases, Containing Same SHIN POONG PHARMACEUTICAL CO., LTD. (KR) 2018-09-06 US claimed
EP-3345910-A1 COMPOUND HAVING EFFECT OF INHIBITING PLATELET AGGREGATION AND SALT THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING THROMBOTIC DISEASES, CONTAINING SAME Shin Poong Pharmaceutical Co., Ltd. (KR) 2018-07-11 EP claimed
EP-3345910-B1 COMPOUND HAVING EFFECT OF INHIBITING PLATELET AGGREGATION AND SALT THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING THROMBOTIC DISEASES, CONTAINING SAME SHIN POONG PHARMACEUTICAL CO LTD (KR) 2023-11-01 EP disclosed
EP-3345910-B1 COMPOUND HAVING EFFECT OF INHIBITING PLATELET AGGREGATION AND SALT THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING THROMBOTIC DISEASES, CONTAINING SAME SHIN POONG PHARMACEUTICAL CO LTD (KR) 2023-11-01 EP disclosed
US-10730886-B2 Compound having effect of inhibiting platelet aggregation and salt thereof, and composition for preventing or treating thrombotic diseases, containing same SHIN POONG PHARMACEUTICAL CO., LTD. (KR) 2020-08-04 US disclosed
US-10730886-B2 Compound having effect of inhibiting platelet aggregation and salt thereof, and composition for preventing or treating thrombotic diseases, containing same SHIN POONG PHARMACEUTICAL CO., LTD. (KR) 2020-08-04 US disclosed
US-20180251472-A1 Compound Having Effect Of Inhibiting Platelet Aggregation And Salt Thereof, And Composition For Preventing Or Treating Thrombotic Diseases, Containing Same SHIN POONG PHARMACEUTICAL CO., LTD. (KR) 2018-09-06 US disclosed
EP-3345910-A1 COMPOUND HAVING EFFECT OF INHIBITING PLATELET AGGREGATION AND SALT THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING THROMBOTIC DISEASES, CONTAINING SAME Shin Poong Pharmaceutical Co., Ltd. (KR) 2018-07-11 EP disclosed
EP-3345910-A1 COMPOUND HAVING EFFECT OF INHIBITING PLATELET AGGREGATION AND SALT THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING THROMBOTIC DISEASES, CONTAINING SAME Shin Poong Pharmaceutical Co., Ltd. (KR) 2018-07-11 EP disclosed
WO-2017039395-A1 COMPOUND HAVING EFFECT OF INHIBITING PLATELET AGGREGATION AND SALT THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING THROMBOTIC DISEASES, CONTAINING SAME 신풍제약 주식회사 2017-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180251472-A1 Compound Having Effect Of Inhibiting Platelet Aggregation And Salt Thereof, And Composition For Preventing Or Treating Thrombotic Diseases, Containing Same PLA2G7, JAK2, PF4 HTT 842/4885SMN1; SMN2 3670/4885LMNA 2948/4885
US-10730886-B2 Compound having effect of inhibiting platelet aggregation and salt thereof, and composition for preventing or treating thrombotic diseases, containing same PLA2G7, JAK2, PF4 HTT 842/4885SMN1; SMN2 3670/4885LMNA 2948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.