Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 4/20 | 0.49 |
| ▸ | TFPI | P10646 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 2/20 | 0.41 |
| ▸ | NPY2R | P49146 | 2/20 | 0.41 |
| ▸ | NPY4R | P50391 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | VIPR2 | P41587 | 2/20 | 0.41 |
| ▸ | VIPR1 | P32241 | 1/20 | 0.41 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29736168 | 0.98 | KEAP1 (0.47) | KEAP1TFPINPY1RNPY2RNPY4R | |
| SCHEMBL29736056 | 0.95 | TFPI (0.46) | KEAP1TFPIOPRL1ECE1GLP1R | |
| SCHEMBL29736145 | 0.95 | TFPI (0.46) | KEAP1TFPIOPRL1ECE1GLP1R | |
| SCHEMBL29595771 | 0.94 | TFPI (0.46) | KEAP1TFPINPY1RNPY2RNPY4R | |
| SCHEMBL29735980 | 0.94 | KEAP1 (0.47) | KEAP1TFPINPY1RNPY2RNPY4R | |
| SCHEMBL29736361 | 0.93 | TFPI (0.44) | KEAP1TFPIOPRL1ECE1GLP1R | |
| SCHEMBL29736243 | 0.92 | PRMT1 (0.46) | KEAP1TFPIOPRL1IL23R | |
| SCHEMBL30433111 | 0.89 | OPRL1 (0.51) | KEAP1TFPIOPRL1VIPR2VIPR1 | |
| SCHEMBL29595332 | 0.89 | TFPI (0.46) | KEAP1TFPI | |
| SCHEMBL29595513 | 0.89 | TFPI (0.43) | KEAP1TFPINPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365217-B2 | Peptides for treating telomere dysfunction-associated diseases and uses thereof | HANGZHOU DUANLI BIOTECHNOLOGY COMPANY LIMITED (CN) | 2022-06-21 | — | — | US | disclosed |