SCHEMBL29736243

C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	PRMT1	Q99873	1/20	0.46

▸	KEAP1	Q14145	1/20	0.46

▸	RAMP3	O60896	6/20	0.45

▸	CALCR	P30988	6/20	0.45

▸	OPRM1	P35372	1/20	0.43

▸	OPRD1	P41143	1/20	0.43

▸	OPRK1	P41145	1/20	0.43

▸	OPRL1	P41146	3/20	0.43

▸	TFPI	P10646	1/20	0.43

▸	IL23R	Q5VWK5	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29736145	0.97	TFPI (0.46)	PRMT1KEAP1RAMP3CALCROPRL1
SCHEMBL29736056	0.97	TFPI (0.46)	PRMT1KEAP1RAMP3CALCROPRL1
SCHEMBL29736168	0.93	KEAP1 (0.47)	PRMT1KEAP1RAMP3CALCRTFPI
SCHEMBL29736066	0.92	KEAP1 (0.49)	KEAP1OPRL1TFPIIL23R
SCHEMBL29736361	0.91	TFPI (0.44)	PRMT1KEAP1RAMP3CALCROPRL1
SCHEMBL29736322	0.90	TFPI (0.48)	RAMP3CALCROPRL1TFPIIL23R
SCHEMBL29736155	0.89	TFPI (0.49)	KEAP1OPRL1TFPI
SCHEMBL31031526	0.89	RAMP3 (0.43)	RAMP3CALCRTFPI
SCHEMBL29736316	0.89	KEAP1 (0.51)	KEAP1RAMP3CALCROPRM1OPRD1
SCHEMBL29735980	0.88	KEAP1 (0.47)	KEAP1OPRL1TFPIIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11365217-B2	Peptides for treating telomere dysfunction-associated diseases and uses thereof	HANGZHOU DUANLI BIOTECHNOLOGY COMPANY LIMITED (CN)	2022-06-21	—	—	US	disclosed