SCHEMBL29736056

C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.46

▸	KEAP1	Q14145	1/20	0.45

▸	PRMT1	Q99873	1/20	0.44

▸	RAMP3	O60896	6/20	0.44

▸	CALCR	P30988	6/20	0.44

▸	OPRL1	P41146	3/20	0.43

▸	ECE1	P42892	1/20	0.42

▸	GLP1R	P43220	1/20	0.42

▸	MUS81	Q96NY9	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29736145	1.00	TFPI (0.46)	TFPIKEAP1PRMT1RAMP3CALCR
SCHEMBL29736168	0.97	KEAP1 (0.47)	TFPIKEAP1PRMT1RAMP3CALCR
SCHEMBL29736243	0.97	PRMT1 (0.46)	TFPIKEAP1PRMT1RAMP3CALCR
SCHEMBL29736066	0.95	KEAP1 (0.49)	TFPIKEAP1OPRL1ECE1GLP1R
SCHEMBL29736361	0.94	TFPI (0.44)	TFPIKEAP1PRMT1RAMP3CALCR
SCHEMBL29736322	0.93	TFPI (0.48)	TFPIRAMP3CALCROPRL1
SCHEMBL29736155	0.93	TFPI (0.49)	TFPIKEAP1OPRL1
SCHEMBL29735980	0.92	KEAP1 (0.47)	TFPIKEAP1OPRL1
SCHEMBL29736084	0.91	PDCD1LG2 (0.46)	TFPIKEAP1RAMP3CALCROPRL1
SCHEMBL29595771	0.89	TFPI (0.46)	TFPIKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11365217-B2	Peptides for treating telomere dysfunction-associated diseases and uses thereof	HANGZHOU DUANLI BIOTECHNOLOGY COMPANY LIMITED (CN)	2022-06-21	—	—	US	disclosed