SCHEMBL29736147

CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(=N)N)[C@@H](C)O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)O)[C@@H](C)O)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	KEAP1	Q14145	2/20	0.47

▸	GLP1R	P43220	6/20	0.46

▸	SCTR	P47872	1/20	0.46

▸	NPY4R	P50391	8/20	0.44

▸	NPY1R	P25929	5/20	0.44

▸	NPY2R	P49146	4/20	0.44

▸	NPY5R	Q15761	4/20	0.44

▸	OPRM1	P35372	1/20	0.44

▸	OPRD1	P41143	1/20	0.44

▸	OPRK1	P41145	1/20	0.44

▸	C5AR1	P21730	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29736307	0.86	C5AR1 (0.52)	KEAP1GLP1RSCTRC5AR1
SCHEMBL30680486	0.85	NPY4R (0.48)	KEAP1GLP1RSCTRNPY4RNPY1R
SCHEMBL30903289	0.85	GLP1R (0.58)	KEAP1GLP1RSCTR
SCHEMBL31452844	0.85	GLP1R (0.47)	KEAP1GLP1RSCTROPRM1OPRD1
Nbi-6024 SCHEMBL29355419	0.84	GLP1R (0.52)	KEAP1GLP1RSCTR
SCHEMBL30262097	0.84	GLP1R (0.59)	KEAP1GLP1RSCTR
SCHEMBL17887955	0.84	C5AR1 (0.47)	KEAP1GLP1RSCTRNPY4RNPY1R
SCHEMBL30851295	0.82	NPY4R (0.52)	GLP1RSCTRNPY4RNPY1RNPY2R
SCHEMBL29973739	0.82	GLP1R (0.51)	KEAP1GLP1RSCTR
SCHEMBL31474484	0.82	NPY4R (0.46)	KEAP1GLP1RSCTRNPY4RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11365217-B2	Peptides for treating telomere dysfunction-associated diseases and uses thereof	HANGZHOU DUANLI BIOTECHNOLOGY COMPANY LIMITED (CN)	2022-06-21	—	—	US	disclosed