Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.60 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23286252 | 1.00 | MAPT (0.60) | MAPTALDH1A1RAB9APTGER4HCAR3 | |
| SCHEMBL20266487 | 0.89 | ALDH1A1 (0.67) | MAPTALDH1A1RAB9APTGER4HCAR3 | |
| SCHEMBL29560026 | 0.89 | ALDH1A1 (0.67) | MAPTALDH1A1RAB9APTGER4HCAR3 | |
| SCHEMBL3717593 | 0.88 | ALDH1A1 (0.60) | MAPTALDH1A1RAB9APTGER4HCAR3 | |
| SCHEMBL31425079 | 0.84 | HCAR3 (0.81) | MAPTALDH1A1RAB9APTGER4HCAR3 | |
| SCHEMBL2314605 | 0.82 | MAPT (0.54) | MAPTALDH1A1RAB9APTGER4HCAR3 | |
| SCHEMBL742213 | 0.82 | ALDH1A1 (0.58) | MAPTALDH1A1RAB9APTGER4HCAR3 | |
| SCHEMBL6947578 | 0.82 | ALDH1A1 (0.47) | MAPTALDH1A1RAB9APTGER4HCAR3 | |
| SCHEMBL1062316 | 0.82 | MAPT (0.47) | MAPTALDH1A1RAB9APTGER4HCAR3 | |
| SCHEMBL30288971 | 0.81 | HCAR3 (0.50) | MAPTALDH1A1RAB9AHCAR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114630823-A | GLP-1R modulating compounds | 吉利德科学公司 | 2022-06-14 | — | — | CN | disclosed |