Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20266487 | 0.92 | ALDH1A1 (0.67) | ALDH1A1MAPTPTGER4RAB9AHCAR3 | |
| SCHEMBL29560026 | 0.92 | ALDH1A1 (0.67) | ALDH1A1MAPTPTGER4RAB9AHCAR3 | |
| SCHEMBL763439 | 0.89 | HCAR3 (0.62) | ALDH1A1MAPTPTGER4RAB9AHCAR3 | |
| SCHEMBL1980059 | 0.88 | KAT2B (0.63) | ALDH1A1MAPTPTGER4RAB9AHCAR3 | |
| SCHEMBL9195511 | 0.88 | HCAR3 (0.62) | ALDH1A1MAPTPTGER4RAB9AHCAR3 | |
| SCHEMBL24492393 | 0.86 | GSTM2 (0.51) | ALDH1A1MAPTPTGER4RAB9AHCAR3 | |
| SCHEMBL17263068 | 0.86 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGER4RAB9AHCAR3 | |
| SCHEMBL6474886 | 0.83 | LMNA (0.57) | ALDH1A1MAPTPTGER4RAB9AHCAR3 | |
| SCHEMBL2019450 | 0.83 | HCAR3 (0.58) | ALDH1A1MAPTPTGER4RAB9AHCAR3 | |
| SCHEMBL22009835 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPTPTGER4RAB9AHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |