Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.45 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.43 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 5/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 7/20 | 0.41 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CTSE | P14091 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493569 | 0.80 | NMUR2 (0.40) | NMUR2NMUR1CALCRLRAMP1 | |
| SCHEMBL30296952 | 0.80 | APLNR (0.44) | APLNRNMUR2NMUR1CALCRLOPRM1 | |
| SCHEMBL31497369 | 0.80 | KEAP1 (0.48) | NMUR2NMUR1CALCRLKEAP1PRMT5 | |
| SCHEMBL30493590 | 0.79 | NMUR2 (0.39) | APLNRNMUR2NMUR1OPRK1 | |
| SCHEMBL30493500 | 0.79 | NMUR2 (0.41) | NMUR2NMUR1CALCRLRAMP1OPRM1 | |
| SCHEMBL30065432 | 0.77 | APLNR (0.49) | APLNROPRM1OPRK1 | |
| SCHEMBL31497340 | 0.77 | KEAP1 (0.54) | NMUR2NMUR1CALCRLKEAP1PRMT5 | |
| SCHEMBL31497333 | 0.77 | CALCRL (0.52) | CALCRLKEAP1PRMT5WDR77 | |
| SCHEMBL31497348 | 0.77 | CALCRL (0.50) | NMUR2NMUR1CALCRLKEAP1PRMT5 | |
| SCHEMBL30933107 | 0.77 | APLNR (0.51) | APLNROPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114767881-A | Preparation and application of tumor microenvironment response type diagnosis and treatment integrated nanoprobe | 山西医科大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114767881-A | Preparation and application of tumor microenvironment response type diagnosis and treatment integrated nanoprobe | 山西医科大学 | 2022-07-22 | — | — | CN | disclosed |