SCHEMBL2974382

SCHEMBL2974382

O=P(O)(O)N1CCOCC1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.50
MMP3 P08254 1/20 0.50
MMP8 P22894 1/20 0.50
GAA P10253 2/20 0.47
MAPT P10636 1/20 0.43
ALPG P10696 1/20 0.42
ANPEP P15144 1/20 0.42
CA12 O43570 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA1 P00915 1/20 0.37
CA9 Q16790 1/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
TP53 P04637 1/20 0.36
HSD17B10 Q99714 1/20 0.34
KDM4E B2RXH2 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29195601 0.91 MMP1 (0.43) MMP1MMP3MMP8GAAMAPT
SCHEMBL329843 0.83 MMP1 (0.50) MMP1MMP3MMP8GAAMAPT
SCHEMBL6882336 0.83 MMP1 (0.38) MMP1MMP3MMP8GAAMAPT
Hydrochloric Acid SCHEMBL11081547 0.81 MMP1 (0.48) MMP1MMP3MMP8GAAMAPT
SCHEMBL1246279 0.79 MMP1 (0.46) MMP1MMP3MMP8GAAMAPT
SCHEMBL7455288 0.79 MMP1 (0.46) MMP1MMP3MMP8GAAMAPT
SCHEMBL3392230 0.78 FDPS (0.33) MMP1MMP3MMP8MAPTSMN1; SMN2
SCHEMBL15536892 0.78 FDPS (0.33) MMP1MMP3MMP8MAPTSMN1; SMN2
SCHEMBL654555 0.78
SCHEMBL1276983 0.77 MAPT (0.46) MMP1MMP3MMP8GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114643075-B Catalyst for synthesizing alkylene carbonate, and preparation method and application thereof 中国石油化工股份有限公司 2023-08-29 CN disclosed
US-8624029-B2 Lipidated imidazoquinoline derivatives GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) 2014-01-07 US disclosed
US-7767842-B2 Class of γδ T cells activators and use thereof INNATE PHARMA SA (FR) 2010-08-03 US disclosed
EP-1328610-B1 PHOSPHATE FLUOROSURFACTANTS FOR USE IN CARBON DIOXIDE UNIV NORTH CAROLINA (US) 2008-07-02 EP disclosed
EP-1328610-B1 PHOSPHATE FLUOROSURFACTANTS FOR USE IN CARBON DIOXIDE UNIV NORTH CAROLINA (US) 2008-07-02 EP disclosed
US-20070249565-A1 Class of Gamma Delta T Cells Activators and Use Thereof INNATE PHARMA S.A. (FR) 2007-10-25 US disclosed
US-7122060-B2 Phosphate fluorosurfactants for use in carbon dioxide THE UNIVERSITY OF NORTH CAROLINA (US) 2006-10-17 US disclosed
EP-1689758-A2 NEW CLASS OF GAMMA DELTA T CELLS ACTIVATORS AND USE THEREOF Innate Pharma (FR) 2006-08-16 EP disclosed
WO-2005054258-A2 NEW CLASS OF GAMMA DELTA T CELLS ACTIVATORS AND USE THEREOF INNATE PHARMA (FR) 2005-06-16 WO disclosed
EP-1328610-A4 PHOSPHATE FLUOROSURFACTANTS FOR USE IN CARBON DIOXIDE UNIV NORTH CAROLINA STATE (US) 2004-09-01 EP disclosed
US-6684525-B2 SURFACTANTS CONTAINING PHOSPHATE GROUP ATTACHED TO FLUOROHYDROCARABON, OR HYBRID WITH PHOSPHATE GROUP ATTACHED TO HYDROCARBON EXHIBIT SOLUBILITY IN CARBON DIOXIDE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2004-02-03 US disclosed
EP-1328610-A1 PHOSPHATE FLUOROSURFACTANTS FOR USE IN CARBON DIOXIDE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2003-07-23 EP disclosed
WO-2002026921-A1 PHOSPHATE FLUOROSURFACTANTS FOR USE IN CARBON DIOXIDE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2002-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249565-A1 Class of Gamma Delta T Cells Activators and Use Thereof CD4, IFNG, NFATC1 MMP1 4597/4885MMP3 3274/4885MMP8 988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.