Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 2/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATF1 | P18846 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14921073 | 1.00 | ASPH (0.46) | ASPHSORT1TSHRCASP1SMN1; SMN2 | |
| SCHEMBL2397361 | 0.87 | ASPH (0.45) | ASPHSORT1P2RX7SYKSMARCA2 | |
| SCHEMBL30064462 | 0.87 | ASPH (0.45) | ASPHSORT1P2RX7SYKSMARCA2 | |
| SCHEMBL19711942 | 0.86 | ASPH (0.40) | ASPHSORT1TSHRCASP1SMN1; SMN2 | |
| SCHEMBL25396796 | 0.85 | SMARCA2 (0.39) | ASPHSMN1; SMN2P2RX7SMARCA2SMARCA4 | |
| SCHEMBL31697155 | 0.84 | TSHR (0.40) | ASPHSORT1TSHRCASP1SMN1; SMN2 | |
| SCHEMBL21823190 | 0.84 | LMNA (0.41) | SMARCA2SMARCA4ATF1NFKB1 | |
| SCHEMBL20639017 | 0.84 | TSHR (0.40) | ASPHSORT1TSHRCASP1SMN1; SMN2 | |
| SCHEMBL28450854 | 0.81 | ASPH (0.46) | ASPHKDM4EKDM8KEAP1NFE2L2 | |
| SCHEMBL30614599 | 0.81 | ASPH (0.46) | ASPHTSHRHPGDKDM4EKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431377-A | Pesticidally active heterocyclic derivatives with sulfoximine containing substituents | 先正达农作物保护股份公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-119285572-A | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119264073-A | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-112839933-B | Pesticidally active benzene-amide and azine-amide compounds | 先正达参股股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-110913858-B | Kinase inhibitors and uses thereof | 戴纳立制药公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-118355004-A | Cyclopropyl- (heteroaryl) -substituted ethylsulfonyl-pyridine derivatives | 勃林格殷格翰动物保健有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-111108107-B | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达参股股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2022159644-A1 | SPIROCYCLIC MDM2 MODULATOR AND USES THEREOF | NEWAVE PHARMACEUTICAL INC. (US) | 2022-07-28 | — | — | WO | disclosed |