Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 13/20 | 0.63 |
| ▸ | GABRP | O00591 | 2/20 | 0.63 |
| ▸ | GABRD | O14764 | 2/20 | 0.63 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.63 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.63 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.63 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.63 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.63 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.63 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.63 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.63 |
| ▸ | GABRE | P78334 | 2/20 | 0.63 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.63 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.63 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.63 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12016685 | 0.80 | KIF11 (0.51) | MAOAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29726993 | 0.78 | KIF11 (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16256557 | 0.78 | KIF11 (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Harman SCHEMBL9754741 | 0.77 | MAOA (1.00) | MAOAGABRPGABRDGABRA1GABRB1 | |
| Harman SCHEMBL29630272 | 0.77 | MAOA (1.00) | MAOAGABRPGABRDGABRA1GABRB1 | |
| Harman SCHEMBL141723 | 0.77 | MAOA (1.00) | MAOAGABRPGABRDGABRA1GABRB1 | |
| Harman SCHEMBL9480937 | 0.77 | MAOA (1.00) | MAOAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL14956337 | 0.76 | BCHE (0.71) | MAOAGABRPGABRDGABRA1GABRB1 | |
| Harman SCHEMBL9717439 | 0.76 | MAOA (0.96) | MAOAGABRPGABRDGABRA1GABRB1 | |
| Harman SCHEMBL3764237 | 0.76 | MAOA (0.96) | MAOAGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382496-B | Substituted pyrido [3,4-b ] indoles for the treatment of cartilage disorders | 赛诺菲 | 2022-08-09 | — | — | CN | disclosed |