Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23362593 | 1.00 | KDM4E (0.37) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL23363199 | 0.85 | ALDH1A1 (0.42) | KDM4ERAB9ATSHRALDH1A1LPAR1 | |
| SCHEMBL30309354 | 0.84 | ADCY10 (0.35) | KDM4ESMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL23384341 | 0.84 | ADCY10 (0.35) | KDM4ESMN1; SMN2RAB9ANPC1CYP1A2 | |
| Hydrochloric Acid SCHEMBL23362550 | 0.83 | ADCY10 (0.35) | KDM4ESMN1; SMN2RAB9ANPC1CYP1A2 | |
| Hydrochloric Acid SCHEMBL29757461 | 0.83 | ADCY10 (0.35) | KDM4ESMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL19715541 | 0.81 | RAB9A (0.47) | KDM4ELMNASMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL23362584 | 0.78 | NPC1 (0.36) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29757487 | 0.78 | NPC1 (0.36) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL24816626 | 0.78 | MAPK1 (0.50) | KDM4ERAB9ANPC1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728168-B | Triazole carbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-115942972-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114728168-A | Triazolecarbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2022-07-08 | — | — | CN | disclosed |