Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23363685 | 1.00 | ALDH1A1 (0.32) | ALDH1A1CYP1A2CYP2C19ADCY10LPAR1 | |
| SCHEMBL23362847 | 0.89 | CYP1A2 (0.32) | ALDH1A1CYP1A2CYP2C19ADCY10KDM4E | |
| SCHEMBL29757475 | 0.89 | CYP1A2 (0.32) | ALDH1A1CYP1A2CYP2C19ADCY10KDM4E | |
| SCHEMBL31345080 | 0.87 | LPAR1 (0.32) | LPAR1 | |
| SCHEMBL29757476 | 0.86 | ADCY10 (0.35) | ALDH1A1ADCY10AAK1KDM4EHPGD | |
| SCHEMBL23363247 | 0.86 | ADCY10 (0.35) | ALDH1A1ADCY10AAK1KDM4EHPGD | |
| SCHEMBL23362584 | 0.83 | NPC1 (0.36) | ALDH1A1CYP1A2CYP2C19ADCY10KDM4E | |
| SCHEMBL29757487 | 0.83 | NPC1 (0.36) | ALDH1A1CYP1A2CYP2C19ADCY10KDM4E | |
| SCHEMBL23363295 | 0.81 | ADCY10 (0.34) | ALDH1A1CYP1A2CYP2C19ADCY10KDM4E | |
| SCHEMBL29757455 | 0.81 | ADCY10 (0.34) | ALDH1A1CYP1A2CYP2C19ADCY10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728168-B | Triazole carbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-114728168-A | Triazolecarbamate pyridylsulfonamides as LPA receptor antagonists and their use | 吉利德科学公司 | 2022-07-08 | — | — | CN | disclosed |