Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | UGCG | Q16739 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974345 | 0.90 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1PKMTSHRSMN1; SMN2 | |
| SCHEMBL28974594 | 0.86 | F11 (0.45) | MAPT | |
| SCHEMBL30680254 | 0.86 | F11 (0.45) | MAPT | |
| SCHEMBL23466576 | 0.86 | F11 (0.45) | MAPT | |
| SCHEMBL23486775 | 0.85 | F11 (0.43) | ALDH1A1L3MBTL1PKMTSHRSMN1; SMN2 | |
| SCHEMBL23466593 | 0.81 | F11 (0.40) | ALDH1A1L3MBTL1PKMTSHRSMN1; SMN2 | |
| SCHEMBL23466596 | 0.81 | F11 (0.40) | ALDH1A1L3MBTL1PKMTSHRSMN1; SMN2 | |
| SCHEMBL28974592 | 0.80 | F11 (0.41) | ALDH1A1L3MBTL1PKMTSHRSMN1; SMN2 | |
| SCHEMBL23486872 | 0.76 | HPGDS (0.42) | — | |
| SCHEMBL28974343 | 0.75 | IRAK4 (0.39) | ALDH1A1L3MBTL1PKMTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |