SCHEMBL29758372

SCHEMBL29758372

Brc1ccc2ccc(-c3ccccn3)nc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.58
CYP1A2 P05177 2/20 0.58
CYP2C19 P33261 1/20 0.58
KDM4E B2RXH2 5/20 0.52
LMNA P02545 4/20 0.52
CCR1 P32246 3/20 0.52
CCR5 P51681 3/20 0.52
CCR8 P51685 3/20 0.52
TP53 P04637 3/20 0.52
ALOX15 P16050 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ALPL P05186 1/20 0.52
HSP90AA1 P07900 1/20 0.52
ALPI P09923 1/20 0.52
ALPG P10696 1/20 0.52
MAPK1 P28482 1/20 0.52
METAP1 P53582 2/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22970594 1.00 HTT (0.58) HTTCYP1A2CYP2C19KDM4ELMNA
SCHEMBL21215962 0.88 KDM4E (0.50) HTTCYP1A2CYP2C19KDM4ELMNA
SCHEMBL21308795 0.88 CYP11B1 (0.47) HTTCYP1A2CYP2C19KDM4ELMNA
SCHEMBL20208052 0.87 KDM4E (0.46) HTTCYP1A2CYP2C19KDM4ELMNA
SCHEMBL24475772 0.82 KDM4E (0.55) HTTCYP1A2CYP2C19KDM4ELMNA
SCHEMBL29746183 0.80 KDM4E (0.61) HTTCYP1A2CYP2C19KDM4ELMNA
SCHEMBL500395 0.80 KDM4E (0.61) HTTCYP1A2CYP2C19KDM4ELMNA
SCHEMBL29496173 0.80 KDM4E (0.61) HTTCYP1A2CYP2C19KDM4ELMNA
SCHEMBL24454171 0.79 KDM4E (0.52) HTTCYP1A2CYP2C19KDM4ELMNA
SCHEMBL13541762 0.79 ALDH1A1 (0.58) HTTCYP1A2KDM4ELMNACCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929687-A Acridine compound, and organic semiconductor layer, organic electronic device and display device comprising same 诺瓦尔德股份有限公司 2022-08-19 CN disclosed