Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407907 | 0.75 | MAPK14 (0.39) | ALDH1A1KMT2ALMNAKDM4EMAPK14 | |
| SCHEMBL3986010 | 0.72 | CA1 (0.44) | CA1CA2CA7CA9CA12 | |
| SCHEMBL5944803 | 0.72 | CA1 (0.44) | CA1CA2CA7CA9CA12 | |
| SCHEMBL5214230 | 0.72 | MAPK14 (0.40) | IDO1ALDH1A1LMNAKDM4EMAPK14 | |
| SCHEMBL9522211 | 0.72 | CA1 (0.44) | CA1CA2CA7CA9CA12 | |
| SCHEMBL2985577 | 0.71 | CYP2A6 (0.41) | ALDH1A1LMNAKDM4EMAPK14TSHR | |
| Hydrochloric Acid SCHEMBL8909847 | 0.70 | HTR6 (0.38) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1114644 | 0.68 | CA12 (0.39) | CA1CA2CA7CA9CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL27452731 | 0.67 | CA1 (0.93) | CA1CA2CA7CA9CA12 | |
| SCHEMBL13470215 | 0.67 | APP (0.44) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286175-A1 | 2-(Pyridin-2-yl)-pyrimidines and Their Use for Controlling Harmful Fungi | GRAMMENOS WASSILIOS | 2010-11-11 | — | — | US | disclosed |
| US-7786043-B2 | 2-(pyridin-2-yl)-pyrimidines and their use for controlling harmful fungi | BASF AKTIENGESELLSCHAFT (DE) | 2010-08-31 | — | — | US | disclosed |
| US-20080027085-A1 | 2-(Pyridin-2-Yl)-Pyrimidines and Their Use for Controlling Harmful Fungi | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027085-A1 | 2-(Pyridin-2-Yl)-Pyrimidines and Their Use for Controlling Harmful Fungi | CBR1, CBR3, CNPY2 | CA1 3979/4885CA2 1594/4885CA7 2555/4885 |
| US-20100286175-A1 | 2-(Pyridin-2-yl)-pyrimidines and Their Use for Controlling Harmful Fungi | CBR1, CBR3, CNPY2 | CA1 3944/4885CA2 1621/4885CA7 2530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.