Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2975907 | 0.70 | CA1 (0.43) | CA1CA2CA12CA7CA9 | |
| Sulfuric Acid SCHEMBL28650112 | 0.68 | PTPRC (0.53) | HTR6SMN1; SMN2FGFR1SRCFGFR2 | |
| SCHEMBL27923561 | 0.66 | SMN1; SMN2 (0.37) | CA1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL8909837 | 0.65 | ACHE (0.45) | HTR6POLBSMN1; SMN2FABP4 | |
| 1,2-Dimethoxybenzene SCHEMBL28862840 | 0.65 | CA1 (0.62) | HTR6POLBCA1CA2CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL10453010 | 0.65 | CA1 (0.62) | HTR6POLBCA1CA2CA12 | |
| SCHEMBL16087656 | 0.62 | SMN1; SMN2 (0.35) | POLBCA1CA2CA12CA9 | |
| SCHEMBL29822548 | 0.62 | HTR6 (0.60) | HTR6CA1CA2CA12CA7 | |
| Guaiacol SCHEMBL3950813 | 0.62 | CA1 (0.78) | HTR6CA1CA2CA12CA7 | |
| SCHEMBL286480 | 0.62 | HTR6 (0.60) | HTR6CA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654114-A | A LITHIUM INTERCALATING AND DEINTERCALATING IN, ZN, MG, GE, SN, PB, SB OR BI OXIDE OR MIXED OXIDE CATHODE, A LITHIUM COBALT METAL OXIDE ANODE CONSISTING OF NI, V, FE, MN, TI OR CU AND A NONAQUEOUS LITHIUM SALT ELECTROLYTE | FUJI PHOTO FILM CO., LTD. (JP) | 1997-08-05 | — | — | US | disclosed |