Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.76 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.76 |
| ▸ | NQO2 | P16083 | 3/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31543713 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL5439854 | 0.86 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL31530479 | 0.86 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL8946916 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL31530480 | 0.86 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL3221458 | 0.85 | KDM4E (0.84) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| Iodomelatonin SCHEMBL163451 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL1311849 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL1774151 | 0.85 | NQO2 (1.00) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 | |
| SCHEMBL8686010 | 0.84 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119633001-A | Application and method of gastrodin in preparation of MT1 agonist with selectivity | 昆明理工大学 | 2025-03-18 | — | — | CN | claimed |
| CN-119633001-A | Application and method of gastrodin in preparation of MT1 agonist with selectivity | 昆明理工大学 | 2025-03-18 | — | — | CN | disclosed |
| CN-118575786-A | Modeling method for insomnia of zebra fish and application of modeling method | 杭州环特优检生物科技有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-117794534-A | Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof | 尤尼根公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20230052740-A1 | MODULATORS OF CIRCADIAN RHYTHMS AND USES THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2023-02-16 | — | — | US | disclosed |
| EP-4021574-A1 | MODULATORS OF CIRCADIAN RHYTHMS AND USES THEREOF | The Regents of the University of California (US) | 2022-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230052740-A1 | MODULATORS OF CIRCADIAN RHYTHMS AND USES THEREOF | MTNR1A, PER2, MTNR1B | MTNR1A 1/4885MTNR1B 3/4885NQO2 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.