SCHEMBL29759482

SCHEMBL29759482

CC1(C)COP(=O)(O)O[C@@H]1c1ccccc1Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.37
TP53 P04637 2/20 0.37
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
RECQL P46063 1/20 0.33
KDM1A O60341 1/20 0.32
RCOR1 Q9UKL0 1/20 0.32
GAA P10253 2/20 0.32
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
ALDH1A1 P00352 2/20 0.31
OPRL1 P41146 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GLA P06280 1/20 0.30
HPGD P15428 1/20 0.30
CASP1 P29466 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5678165 1.00 PTGS2 (0.37) PTGS2TP53KMT2APOLBTSHR
SCHEMBL2026167 1.00 PTGS2 (0.37) PTGS2TP53KMT2APOLBTSHR
SCHEMBL29590612 1.00 PTGS2 (0.37) PTGS2TP53KMT2APOLBTSHR
SCHEMBL547802 1.00 PTGS2 (0.37) PTGS2TP53KMT2APOLBTSHR
SCHEMBL547467 0.89 HTR2A (0.35) TP53KMT2ATSHRGAAHTR2A
SCHEMBL1682788 0.86 TP53 (0.38) PTGS2TP53KMT2APOLBTSHR
SCHEMBL5678327 0.84 PTGS2 (0.35) PTGS2TP53KMT2APOLBTSHR
SCHEMBL28361354 0.84 HTR5A (0.31) HTR2AHTR2C
SCHEMBL28194083 0.84 HTR5A (0.31) HTR2AHTR2C
SCHEMBL28194084 0.84 HTR5A (0.31) HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4045615-A1 AN INDUSTRIAL PROCESS FOR RESOLUTION OF CHLOCYPHOS Hikal Limited (IN) 2022-08-24 EP disclosed