Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678165 | 1.00 | PTGS2 (0.37) | PTGS2TP53KMT2APOLBTSHR | |
| SCHEMBL29759482 | 1.00 | PTGS2 (0.37) | PTGS2TP53KMT2APOLBTSHR | |
| SCHEMBL2026167 | 1.00 | PTGS2 (0.37) | PTGS2TP53KMT2APOLBTSHR | |
| SCHEMBL29590612 | 1.00 | PTGS2 (0.37) | PTGS2TP53KMT2APOLBTSHR | |
| SCHEMBL547467 | 0.89 | HTR2A (0.35) | TP53KMT2ATSHRGAAHTR2A | |
| SCHEMBL1682788 | 0.86 | TP53 (0.38) | PTGS2TP53KMT2APOLBTSHR | |
| SCHEMBL5678327 | 0.84 | PTGS2 (0.35) | PTGS2TP53KMT2APOLBTSHR | |
| SCHEMBL28361354 | 0.84 | HTR5A (0.31) | HTR2AHTR2C | |
| SCHEMBL28194083 | 0.84 | HTR5A (0.31) | HTR2AHTR2C | |
| SCHEMBL28194084 | 0.84 | HTR5A (0.31) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107602464-B | Method for preparing biaryl quinoline antibiotics by optical resolution | 宜昌人福药业有限责任公司 | 2020-02-18 | — | — | CN | claimed |
| CN-104876856-A | Method for preparing (R)-(+)-3-piperidinamine dihydrochloride by using resolution method | HEBEI KAILIANG BIOTECHNOLOGY CO LTD | 2015-09-02 | — | — | CN | claimed |
| CN-104829459-A | Splitting method for preparing (R)-(+)-1-naphthyl ethylamine | HEBEI CHIRAL CHEMISTRY AND BIOTECHNOLOGY CO LTD | 2015-08-12 | — | — | CN | claimed |
| CN-103755582-B | Preparation method according to D-serine through splitting method | UNIV HEBEI SCIENCE & TECH | 2015-04-08 | — | — | CN | claimed |
| CN-103755582-A | Preparation method according to D-serine through splitting method | UNIV HEBEI SCIENCE & TECH | 2014-04-30 | — | — | CN | claimed |
| CN-102070469-B | Resolution method for preparing optically pure metoprolol | UNIV HEBEI SCIENCE & TECH | 2013-11-20 | — | — | CN | claimed |
| CN-101792398-B | Method for preparing optical pure p-hydroxy phenyl glycine by separation method | UNIV HEBEI SCIENCE & TECH | 2013-06-26 | — | — | CN | claimed |
| CN-102070469-A | Resolution method for preparing optically pure metoprolol | UNIV HEBEI SCIENCE & TECH | 2011-05-25 | — | — | CN | claimed |
| CN-101792398-A | Method for preparing optical pure p-hydroxy phenyl glycine by separation method | HEBEI UNIVERSITY OF SCIENCE & TECHNOLOGY | 2010-08-04 | — | — | CN | claimed |
| US-5663354-A | Process for preparing enantiomerically pure 6-[(4-chlorophenyl) (1H-1,2,4-triazol-1-yl) methyl]-1-methyl-1H-benzotrizole | JANSSEN PHARMACEUTICA, N.V. (BE) | 1997-09-02 | — | — | US | claimed |
| EP-0668861-A1 | PROCESS FOR PREPARING ENANTIOMERICALLY PURE 6- (4-CHLOROPHENYL)(1H --TRIAZOL-1,2,4-TRIAZOL-1-YL)METHYL]-1-METHYL-1H --BENZOTRIAZOLE | JANSSEN PHARMACEUTICA N.V. (BE) | 1995-08-30 | — | — | EP | claimed |
| WO-1994011364-A1 | PROCESS FOR PREPARING ENANTIOMERICALLY PURE 6-[(4-CHLOROPHENYL)(1H^_-TRIAZOL-1,2,4-TRIAZOL-1-YL)METHYL]-1-METHYL-1H^_-BENZOTRIAZOLE | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-05-26 | — | — | WO | claimed |
| CN-110317212-B | Synthesis of polycyclic carbamoylpyridone compounds | 吉利德科学公司 | 2022-10-21 | — | — | CN | disclosed |
| EP-4045615-A1 | AN INDUSTRIAL PROCESS FOR RESOLUTION OF CHLOCYPHOS | Hikal Limited (IN) | 2022-08-24 | — | — | EP | disclosed |
| CN-114394983-A | Synthesis of polycyclic carbamoylpyridone compounds | 吉利德科学公司 | 2022-04-26 | — | — | CN | disclosed |
| WO-2021074778-A1 | AN INDUSTRIAL PROCESS FOR RESOLUTION OF CHLOCYPHOS | HIKAL LIMITED (IN) | 2021-04-22 | — | — | WO | disclosed |
| US-4968837-A | Resolution of racemic mixtures | ETHYL CORPORATION (US) | 1990-11-06 | — | — | US | disclosed |
| WO-1989012445-A1 | METHOD AND COMPOSITIONS FOR TREATMENT OF PARKINSONISM SYNDROME IN MAMMALS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-12-28 | — | — | WO | disclosed |
| US-4885308-A | ADMINISTERING DOPAMINERGIC TETRALIN DERIVATIVE | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0180276-B1 | DIOXAPHOSPHORINANES, THEIR PREPARATION AND USE FOR RESOLVING OPTICALLY ACTIVE COMPOUNDS | STAMICARBON B.V. (NL) | 1988-12-28 | — | — | EP | disclosed |