Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.41 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28859625 | 0.76 | SMN1; SMN2 (0.51) | — | |
| SCHEMBL19070416 | 0.75 | VNN1 (0.41) | VNN1PIK3CAPIK3CDPIK3R2PIK3CB | |
| SCHEMBL19070303 | 0.75 | PRMT5 (0.54) | VNN1PIK3CAPIK3CDPIK3R2PIK3CB | |
| SCHEMBL7449265 | 0.74 | PDE10A (0.47) | VNN1PIK3CAPIK3CDPIK3R2PIK3CB | |
| SCHEMBL24135776 | 0.73 | ALOX5AP (0.47) | VNN1PIK3CAPIK3CDPIK3R2PIK3CB | |
| SCHEMBL7449259 | 0.73 | PDE10A (0.48) | VNN1PIK3CAPIK3CDPIK3R2PIK3CB | |
| SCHEMBL26790639 | 0.71 | ACHE (0.54) | — | |
| SCHEMBL16345930 | 0.70 | PRMT5 (0.47) | VNN1PIK3CAPIK3CDPIK3R2PIK3CB | |
| SCHEMBL19070285 | 0.68 | VNN1 (0.46) | VNN1ALOX5APFEN1CCKBRPRMT5 | |
| SCHEMBL28132587 | 0.68 | CA12 (0.58) | VNN1PIK3CAPIK3CDPIK3R2PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263545-A1 | PRMTS INHIBITORS | Amgen Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022132914-A1 | PRMTS INHIBITORS | AMGEN INC. (US) | 2022-06-23 | — | — | WO | disclosed |