Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30921003 | 0.82 | L3MBTL1 (0.51) | NPC1RAB9AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL13744784 | 0.80 | L3MBTL1 (0.73) | ACHEHSD11B1NPC1RAB9AHPGD | |
| SCHEMBL26790988 | 0.79 | KDM5A (0.50) | HPGDNAMPTL3MBTL1KDM5A | |
| SCHEMBL27491158 | 0.78 | L3MBTL1 (0.47) | ALDH1A1SMN1; SMN2NAMPTL3MBTL1KDM5A | |
| SCHEMBL28859625 | 0.78 | SMN1; SMN2 (0.51) | NPC1RAB9AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL22840143 | 0.77 | ACHE (0.51) | ACHEHSD11B1NPC1RAB9AHPGD | |
| SCHEMBL20460496 | 0.76 | HSD11B1 (0.51) | ACHEHSD11B1NPC1RAB9AHPGD | |
| SCHEMBL13450099 | 0.76 | HSD11B1 (0.61) | ACHEHSD11B1NPC1RAB9AHPGD | |
| SCHEMBL17546293 | 0.76 | HSD11B1 (0.61) | ACHEHSD11B1NPC1RAB9AHPGD | |
| SCHEMBL27672802 | 0.76 | NAMPT (0.43) | NAMPTL3MBTL1KDM4EKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220247-A1 | LRRK2 INHIBITORS | INTERLINE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |