SCHEMBL2976177

SCHEMBL2976177

O=c1cccc2n(Cc3ccccc3)c3ccccc3cc1-2

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.53
KDM4E B2RXH2 2/20 0.53
ALDH1A1 P00352 2/20 0.53
GAA P10253 1/20 0.53
HTT P42858 1/20 0.53
CCR2 P41597 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
LMNA P02545 1/20 0.52
ESR1 P03372 7/20 0.47
MAPK1 P28482 1/20 0.44
P2RX4 Q99571 1/20 0.44
PLA2G10 O15496 1/20 0.43
PTGS2 P35354 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2975140 0.83 HPGD (0.51) HPGDKDM4EALDH1A1GAAHTT
SCHEMBL2969653 0.82 BRD4 (0.46) HPGDKDM4EALDH1A1GAAHTT
SCHEMBL4673338 0.81 L3MBTL1 (0.62) KDM4EALDH1A1CCR2KMT2AMEN1
SCHEMBL8140897 0.80 L3MBTL1 (0.47) HPGDKDM4EALDH1A1GAAHTT
SCHEMBL10767783 0.79 HEXA (0.42) HPGDKDM4EALDH1A1GAAHTT
SCHEMBL195008 0.77 ALDH1A1 (0.49) HPGDKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL10769824 0.76 ALDH1A1 (0.53) HPGDKDM4EALDH1A1HTTSMN1; SMN2
SCHEMBL10767848 0.75 MEN1 (0.43) KDM4EALDH1A1HTTKMT2AMEN1
SCHEMBL9020238 0.75 KMT2A (0.35) HPGDKDM4EALDH1A1GAAHTT
SCHEMBL4887683 0.74 L3MBTL1 (0.61) ALDH1A1CCR2SMN1; SMN2LMNAESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108794497-B Novel N-benzyl acridone alkaloid and preparation method and application thereof 江西中医药大学 2020-09-22 CN claimed
US-5069999-A PRESENSITIZED FUJI PHOTO FILM CO., LTD. (JP) 1991-12-03 US claimed
EP-1509601-B1 FLUORESCENT DETECTION OF PEROXIDASE ENZYMES LUMIGEN INC (US) 2012-12-05 EP disclosed
US-7776507-B2 Photosensitive paste and manufacturing method of member for display panel TORAY INDUSTRIES, INC. (JP) 2010-08-17 US disclosed
US-20090035452-A1 Photosensitive paste and manufacturing method of member for display panel TORAY INDUSTRIES, INC. (JP) 2009-02-05 US disclosed
EP-1509601-A4 FLUORESCENT DETECTION OF PEROXIDASE ENZYMES LUMIGEN INC (US) 2009-01-14 EP disclosed
US-6897036-B2 Fluorescent detection of peroxidase enzymes LUMIGEN, INC. (US) 2005-05-24 US disclosed
EP-1509601-A1 FLUORESCENT DETECTION OF PEROXIDASE ENZYMES LUMIGEN, INC. (US) 2005-03-02 EP disclosed
US-20030232405-A1 Fluorescent detection of peroxidase enzymes LUMIGEN INC. 2003-12-18 US disclosed
WO-2003104447-A1 FLUORESCENT DETECTION OF PEROXIDASE ENZYMES LUMIGEN, INC. (US) 2003-12-18 WO disclosed
US-5069999-A PRESENSITIZED FUJI PHOTO FILM CO., LTD. (JP) 1991-12-03 US disclosed