Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 7/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18200291 | 0.82 | NOS3 (0.38) | GRIN1GRIN2BNOS3NOS1NOS2 | |
| SCHEMBL16815694 | 0.80 | CCR1 (0.39) | GRIN1GRIN2BNOS3NOS1NOS2 | |
| SCHEMBL1154350 | 0.80 | LOXL2 (0.43) | GRIN1GRIN2BNOS3NOS1NOS2 | |
| SCHEMBL20893799 | 0.80 | GRIN1 (0.38) | GRIN1GRIN2BNOS3NOS1NOS2 | |
| SCHEMBL19932063 | 0.80 | NOS3 (0.37) | GRIN1GRIN2BNOS3NOS1NOS2 | |
| SCHEMBL30026942 | 0.79 | GRIN1 (0.36) | GRIN1GRIN2BNOS3NOS1NOS2 | |
| SCHEMBL22905296 | 0.77 | FFAR1 (0.36) | GRIN1GRIN2BNOS3NOS1NOS2 | |
| SCHEMBL21567109 | 0.77 | GRIN1 (0.36) | GRIN1GRIN2BNOS3NOS1NOS2 | |
| SCHEMBL990352 | 0.77 | KCNH2 (0.52) | NOS3NOS1NOS2FFAR1ALDH1A1 | |
| SCHEMBL5103633 | 0.76 | MEN1 (0.39) | GRIN1GRIN2BNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288424-A1 | NOVEL HETEROARYL-SUBSTITUTED IMIDAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167631-A1 | NOVEL HETEROARYL-SUBSTITUTED IMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-08-11 | — | — | WO | disclosed |