Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974108 | 0.86 | KEAP1 (0.39) | LPLLIPG | |
| SCHEMBL29763543 | 0.83 | — | — | |
| SCHEMBL632831 | 0.82 | EGFR (0.31) | LPLLIPG | |
| SCHEMBL993845 | 0.77 | LPL (0.36) | LPLLIPG | |
| SCHEMBL26262428 | 0.74 | KDM4E (0.39) | — | |
| SCHEMBL21542750 | 0.71 | IDO1 (0.37) | LPLLIPG | |
| SCHEMBL1464811 | 0.71 | DAO (0.49) | — | |
| SCHEMBL26262526 | 0.69 | KIF11 (0.36) | — | |
| SCHEMBL1465764 | 0.68 | KIF11 (0.34) | — | |
| SCHEMBL25064046 | 0.67 | LPL (0.37) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288424-A1 | NOVEL HETEROARYL-SUBSTITUTED IMIDAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167631-A1 | NOVEL HETEROARYL-SUBSTITUTED IMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-08-11 | — | — | WO | disclosed |