SCHEMBL29763558

SCHEMBL29763558

CN1C(=O)C(c2ccccc2)(c2ccccc2)NC1=S

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.58
CNR1 P21554 8/20 0.51
POLB P06746 2/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.46
TDP1 Q9NUW8 1/20 0.43
CACNA1F O60840 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
HTR2A P28223 1/20 0.43
HRH1 P35367 1/20 0.43
SCN1A P35498 1/20 0.43
SCN4A P35499 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
CACNA1D Q01668 1/20 0.43
KCNH2 Q12809 1/20 0.43
CACNA1S Q13698 1/20 0.43
CACNA1C Q13936 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20291002 0.87 CNR1 (0.51) FAAHCNR1
SCHEMBL4527211 0.87 FAAH (0.48) FAAHCNR1POLBTDP1
SCHEMBL4115606 0.87 CNR1 (0.51) FAAHCNR1
SCHEMBL4525980 0.84 FAAH (0.45) FAAHCNR1POLBHRH1
SCHEMBL3100182 0.83 TSHR (0.59) FAAHPOLBTSHRCYP2C19TDP1
SCHEMBL18920839 0.83 CNR1 (0.50) FAAHCNR1
SCHEMBL4732724 0.83 CNR1 (0.47) FAAHCNR1POLB
SCHEMBL4520761 0.83 CNR1 (0.47) FAAHCNR1POLB
SCHEMBL4237258 0.81 ALDH1A1 (0.56) FAAHPOLBTSHRCYP2C19ALDH1A1
SCHEMBL4511496 0.81 FAAH (0.43) FAAHCNR1POLBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078170-A1 Pan-Neutralizing SARS-CoV-2 mAb Composition and Methods of Treatment Thereof WASHINGTON UNIVERSITY (US) 2026-03-19 US disclosed
CN-113785386-B Wire bonding apparatus, method for manufacturing semiconductor device, and semiconductor device 株式会社新川 2025-01-10 CN disclosed
US-20240228596-A1 PAN-SPECIFIC CORONA VIRUS BINDERS UNIVERSITEIT GENT (BE) 2024-07-11 US disclosed
CN-118103395-A Pan-specific coronavirus binding agents VIB研究所 2024-05-28 CN disclosed
CN-117794566-A Sha Bei viral binding agents VIB研究所 2024-03-29 CN disclosed
US-20240101647-A1 SARBECOVIRUS BINDERS VIB VZW (BE) 2024-03-28 US disclosed
EP-4337688-A1 PAN-SPECIFIC CORONA VIRUS BINDERS VIB VZW (BE) 2024-03-20 EP disclosed
EP-4288095-A1 SARBECOVIRUS BINDERS VIB VZW (BE) 2023-12-13 EP disclosed
WO-2022238550-A1 PAN-SPECIFIC CORONA VIRUS BINDERS VIB VZW (BE) 2022-11-17 WO disclosed
WO-2022167666-A1 SARBECOVIRUS BINDERS VIB VZW (BE) 2022-08-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078170-A1 Pan-Neutralizing SARS-CoV-2 mAb Composition and Methods of Treatment Thereof ACE2, IGLV6-57, TMPRSS2 FAAH 2275/4885CNR1 3891/4885POLB 1644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.