Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30136554 | 0.84 | AR (0.53) | CA1CA2CA9NR3C1PGR | |
| SCHEMBL1018276 | 0.84 | AR (0.53) | CA1CA2CA9NR3C1PGR | |
| SCHEMBL29764403 | 0.83 | ALOX5AP (0.43) | CA1CA2CA9NR3C1PGR | |
| SCHEMBL31492457 | 0.78 | AHR (0.60) | CA1CA2NR3C1PGRNR3C2 | |
| SCHEMBL29764415 | 0.78 | NR3C1 (0.39) | CA1CA2CA9NR3C1PGR | |
| SCHEMBL29764402 | 0.78 | CA2 (0.40) | CA1CA2CA9ALOX5APFEN1 | |
| SCHEMBL29764439 | 0.77 | CA2 (0.48) | CA1CA2CA9NR3C1PGR | |
| SCHEMBL1080972 | 0.76 | CA2 (0.61) | CA1CA2CA9ALOX5APFEN1 | |
| SCHEMBL29764456 | 0.76 | AHR (0.44) | NR3C1PGRNR3C2ARPDPK1 | |
| SCHEMBL8347239 | 0.74 | CA2 (0.58) | CA1CA2CA9ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634155-A1 | RBM39 SULFONAMIDE INHIBITORS | Recursion Pharmaceuticals, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024129634-A1 | RBM39 SULFONAMIDE INHIBITORS | RECURSION PHARMACEUTICALS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |