Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29764346 | 0.83 | CA1 (0.47) | ALOX5APFEN1NR3C1PGRNR3C2 | |
| SCHEMBL30136554 | 0.74 | AR (0.53) | NR3C1PGRNR3C2ARACLY | |
| SCHEMBL1018276 | 0.74 | AR (0.53) | NR3C1PGRNR3C2ARACLY | |
| Hydrochloric Acid SCHEMBL26614912 | 0.73 | AR (0.51) | NR3C1PGRNR3C2ARACLY | |
| SCHEMBL31492457 | 0.72 | AHR (0.60) | NR3C1PGRNR3C2ARPDPK1 | |
| SCHEMBL6089266 | 0.70 | AHR (0.46) | NR3C1ACLYPDPK1REN | |
| SCHEMBL29764456 | 0.69 | AHR (0.44) | NR3C1PGRNR3C2ARPTGES2 | |
| SCHEMBL29764415 | 0.68 | NR3C1 (0.39) | NR3C1PGRNR3C2ARPTGES2 | |
| SCHEMBL5659490 | 0.68 | AHR (0.47) | NR3C1PGRNR3C2ARACLY | |
| SCHEMBL29764439 | 0.68 | CA2 (0.48) | NR3C1PGRNR3C2ARCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |