Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | TPX2 | Q9ULW0 | 2/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5187984 | 1.00 | KEAP1 (0.49) | KEAP1CSNK2A2CSNK2BCSNK2A1AURKA | |
| SCHEMBL27205515 | 0.85 | CSNK2A2 (0.46) | KEAP1CSNK2A2CSNK2BCSNK2A1AURKA | |
| SCHEMBL11660386 | 0.84 | KEAP1 (0.55) | KEAP1AURKATPX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL15826472 | 0.84 | P2RX7 (0.41) | CSNK2A2CSNK2BCSNK2A1AURKATPX2 | |
| SCHEMBL22927191 | 0.82 | AURKA (0.38) | CSNK2A2CSNK2BCSNK2A1AURKATPX2 | |
| SCHEMBL16382729 | 0.80 | NR4A2 (0.50) | ALDH1A1SMN1; SMN2KDM4EKMT2A | |
| Acetic Acid SCHEMBL27953393 | 0.79 | CREBBP (0.41) | CSNK2A2CSNK2BCSNK2A1AURKATPX2 | |
| SCHEMBL2768819 | 0.78 | KEAP1 (0.49) | KEAP1CSNK2A2CSNK2BCSNK2A1AURKA | |
| SCHEMBL2382490 | 0.78 | KEAP1 (0.49) | KEAP1AURKATPX2SMN1; SMN2BTK | |
| SCHEMBL5187097 | 0.78 | KEAP1 (0.49) | KEAP1AURKATPX2SMN1; SMN2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |