Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCGR3B | O75015 | 1/20 | 0.46 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.46 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 4/20 | 0.45 |
| ▸ | NOS2 | P35228 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995322 | 0.84 | MEN1 (0.44) | FCGR3BFCGR1AFCGR2AFFAR1KDM4E | |
| SCHEMBL5153716 | 0.82 | MAOA (0.49) | NOS1NOS2HIF1AHDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL866314 | 0.80 | MAOA (0.47) | NOS1NOS2HIF1AHDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL4954157 | 0.80 | MAOA (0.47) | NOS1NOS2HIF1AHDAC8HDAC6 | |
| SCHEMBL33766 | 0.80 | APP (0.48) | FCGR3BFCGR1AFCGR2AMEN1ALDH1A1 | |
| SCHEMBL2993170 | 0.79 | CYP19A1 (0.55) | NOS1NOS2HIF1AHDAC8HDAC6 | |
| SCHEMBL2990472 | 0.78 | FFAR1 (0.39) | NOS1HIF1AHDAC8HDAC6FFAR1 | |
| Hydrochloric Acid SCHEMBL21056194 | 0.78 | APP (0.47) | FCGR3BFCGR1AFCGR2AKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL8420321 | 0.78 | APP (0.47) | FCGR3BFCGR1AFCGR2AKDM4EMEN1 | |
| SCHEMBL2940046 | 0.78 | HIF1A (0.61) | HIF1AKDM4EMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE41549-E1 | Dyes for keratin fibers, the dyes containing n-benzyl-p-phenylenediamine derivatives and novel n-benzyl-p-phenylenediamine derivatives | WELLA AG (DE) | 2010-08-24 | — | — | US | disclosed |
| EP-1493731-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and these derivatives | Wella Aktiengesellschaft (DE) | 2005-01-05 | — | — | EP | disclosed |
| US-6689174-B2 | FOR OXIDATIVELY DYEING HUMAN HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-10 | — | — | US | disclosed |
| US-20020166181-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and novel n-benzyl-p-phenylenediamine-derivatives | CHASSOT LAURENT (CH) | 2002-11-14 | — | — | US | disclosed |
| EP-1226107-A1 | N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES CONTAINING COLOURING AGENTS FOR KERATIN FIBRES AND NOVEL N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2002-07-31 | — | — | EP | disclosed |
| WO-2002018318-A1 | N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES CONTAINING COLOURING AGENTS FOR KERATIN FIBRES AND NOVEL N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020166181-A1 | N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and novel n-benzyl-p-phenylenediamine-derivatives | KRT18, KPNB1, VIM | FCGR3B 4828/4885FCGR1A 4761/4885FCGR2A 4799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.