Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4954157 | 0.98 | MAOA (0.47) | MAOAMAOBHTTHIF1AKDM4E | |
| Hydrochloric Acid SCHEMBL866314 | 0.98 | MAOA (0.47) | MAOAMAOBHTTHIF1AKDM4E | |
| SCHEMBL2993170 | 0.92 | CYP19A1 (0.55) | MAOAMAOBHTTHIF1AKDM4E | |
| SCHEMBL31438690 | 0.89 | MAOA (0.48) | MAOAMAOBHTTKDM4EMEN1 | |
| SCHEMBL2940046 | 0.87 | HIF1A (0.61) | MAOAMAOBHIF1AKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL2987245 | 0.86 | HIF1A (0.60) | MAOAMAOBHIF1AKDM4EMEN1 | |
| SCHEMBL564987 | 0.85 | HTT (0.64) | MAOAMAOBHTTMEN1ALDH1A1 | |
| SCHEMBL2551581 | 0.84 | NOS1 (0.39) | MAOAMAOBHTTHIF1AKDM4E | |
| SCHEMBL2987758 | 0.83 | HIF1A (0.63) | HIF1AKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL2987091 | 0.83 | NOS1 (0.56) | MAOAMAOBHTTALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222432-A1 | TEST STRIP USING FORMALDEHYDE OR PEROXIDE, FROM AMONG SARCOSINE METABOLITES, FOR DIAGNOSING PROSTATE CANCER, AND METHOD FOR DIAGNOSING PROSTATE CANCER USING SAME | CSQUARE CO., LTD (KR) | 2016-08-04 | — | — | US | claimed |
| US-10558089-B2 | Photoalignment composition | ROLIC AG (CH) | 2020-02-11 | — | — | US | disclosed |
| US-20170255064-A1 | PHOTOALIGNMENT COMPOSITION | ROLIC AG (CH) | 2017-09-07 | — | — | US | disclosed |
| US-20160222432-A1 | TEST STRIP USING FORMALDEHYDE OR PEROXIDE, FROM AMONG SARCOSINE METABOLITES, FOR DIAGNOSING PROSTATE CANCER, AND METHOD FOR DIAGNOSING PROSTATE CANCER USING SAME | CSQUARE CO., LTD (KR) | 2016-08-04 | — | — | US | disclosed |
| US-9145398-B2 | Methods of treating CXCR4-expressing cancers | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2015-09-29 | — | — | US | disclosed |
| WO-2015050366-A1 | TEST STRIP USING FORMALDEHYDE OR PEROXIDE, FROM AMONG SARCOSINE METABOLITES, FOR DIAGNOSING PROSTATE CANCER, AND METHOD FOR DIAGNOSING PROSTATE CANCER USING SAME | 주식회사 씨스퀘어 | 2015-04-09 | — | — | WO | disclosed |
| US-20140303170-A1 | COMPOUNDS FOR TREATING DISEASE, FOR ADMINISTERING, AND FOR PHARMACEUTICAL COMPOSITIONS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2014-10-09 | — | — | US | disclosed |
| US-8785490-B2 | Compounds for treating disease, for administering, and for pharmaceutical compositions | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130059852-A1 | COMPOUNDS FOR TREATING DISEASE, FOR ADMINISTERING, AND FOR PHARMACEUTICAL COMPOSITIONS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| WO-2011127333-A2 | COMPOUNDS FOR TREATING DISEASE, FOR ADMINISTERING, AND FOR PHARMACEUTICAL COMPOSITIONS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2011-10-13 | — | — | WO | disclosed |
| US-7422609-B2 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2008-09-09 | — | — | US | disclosed |
| US-7422609-B2 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2008-09-09 | — | — | US | disclosed |
| US-20070011824-A1 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011824-A1 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739085-A1 | Cosmetic composition containing a double para-phenylenediamines joined by an aromatic group and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739085-A1 | Cosmetic composition containing a double para-phenylenediamines joined by an aromatic group and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739085-A1 | Cosmetic composition containing a double para-phenylenediamines joined by an aromatic group and use in dyeing | L'OREAL (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011824-A1 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | KRT18, CDC73, JUP | MAOA 577/4885MAOB 597/4885HTT 4081/4885 |
| US-20130059852-A1 | COMPOUNDS FOR TREATING DISEASE, FOR ADMINISTERING, AND FOR PHARMACEUTICAL COMPOSITIONS | PKD1, PCSK9, SLC10A1 | MAOA 350/4885MAOB 210/4885HTT 14/4885 |
| US-20140303170-A1 | COMPOUNDS FOR TREATING DISEASE, FOR ADMINISTERING, AND FOR PHARMACEUTICAL COMPOSITIONS | PKD1, PCSK9, SLC10A1 | MAOA 350/4885MAOB 210/4885HTT 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.