Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GALK1 | P51570 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20972428 | 1.00 | MAPT (0.35) | MAPTALOX15SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7036431 | 0.87 | MAPT (0.37) | MAPTALOX15SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL20972468 | 0.85 | CYP2A6 (0.33) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL29767571 | 0.84 | ENPP3 (0.35) | MAPTALOX15SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL20972445 | 0.84 | ENPP3 (0.35) | MAPTALOX15SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL20972422 | 0.83 | RAB9A (0.34) | MAPTALOX15SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29767591 | 0.83 | RAB9A (0.34) | MAPTALOX15SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL20972455 | 0.82 | GPR55 (0.30) | — | |
| SCHEMBL29767650 | 0.82 | GPR55 (0.30) | — | |
| SCHEMBL20972487 | 0.81 | CYP2A6 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111372954-B | Preparation of polyethylene (bis) silicon-bridged metallocenes with broad molecular weight distribution and molecular weight | 埃克森美孚化学专利公司 | 2022-06-28 | — | — | CN | disclosed |