Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679018 | 0.79 | DPP4 (0.39) | CYP2A6DPP4PDCD1CD274ALDH1A1 | |
| SCHEMBL8679597 | 0.78 | DPP4 (0.42) | CYP2A6DPP4PDCD1CD274ALDH1A1 | |
| SCHEMBL127574 | 0.78 | MAPK1 (0.41) | CYP2A6DPP4PDCD1CD274ALDH1A1 | |
| SCHEMBL11108795 | 0.76 | CYP2A6 (0.54) | CYP2A6DPP4ALDH1A1HSD17B10HPGD | |
| SCHEMBL16387926 | 0.74 | PDCD1 (0.39) | CYP2A6DPP4PDCD1CD274ALDH1A1 | |
| SCHEMBL9241713 | 0.74 | ESR1 (0.36) | CYP2A6DPP4PDCD1CD274ALDH1A1 | |
| SCHEMBL8679607 | 0.73 | DPP4 (0.38) | CYP2A6DPP4PDCD1CD274ALDH1A1 | |
| SCHEMBL677798 | 0.72 | MAPK1 (0.40) | CYP2A6DPP4PDCD1CD274ALDH1A1 | |
| SCHEMBL8679296 | 0.72 | DPP4 (0.37) | CYP2A6DPP4PDCD1CD274ALDH1A1 | |
| SCHEMBL27593989 | 0.72 | SMN1; SMN2 (0.35) | CYP2A6DPP4PDCD1CD274ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11414665-B2 | Nucleic acid, composition and conjugate comprising the same, and preparation method and use thereof | Suzhou Ribo Life Science Co., Ltd. (CN) | 2022-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11414665-B2 | Nucleic acid, composition and conjugate comprising the same, and preparation method and use thereof | NSUN2, RNGTT, ADAR | CYP2A6 1589/4885DPP4 4560/4885PDCD1 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.