SCHEMBL677798

SCHEMBL677798

CCC(C)(C)c1ccc2cccccc1-2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CASP3 P42574 2/20 0.40
SENP8 Q96LD8 2/20 0.40
SENP7 Q9BQF6 2/20 0.40
SENP6 Q9GZR1 2/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
RAB9A P51151 1/20 0.40
ATM Q13315 1/20 0.40
PTGS2 P35354 1/20 0.37
DPP4 P27487 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
BCL2L1 Q07817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127574 0.94 MAPK1 (0.41) MAPK1SMN1; SMN2CASP3SENP8SENP7
Sulfuric Acid SCHEMBL6511524 0.88 PTGS2 (0.41) MAPK1SMN1; SMN2CASP3SENP8SENP7
SCHEMBL27797465 0.83 ABL1 (0.44) MAPK1SMN1; SMN2CASP3SENP8SENP7
SCHEMBL6342144 0.80 PPARG (0.35) MAPK1SMN1; SMN2CASP3SENP8SENP7
SCHEMBL6342141 0.80 SMN1; SMN2 (0.41) MAPK1SMN1; SMN2CASP3SENP8SENP7
SCHEMBL9695975 0.79 PDCD1 (0.37) MAPK1SMN1; SMN2CASP3SENP8SENP7
SCHEMBL10438750 0.79 PDCD1 (0.37) MAPK1SMN1; SMN2CASP3SENP8SENP7
SCHEMBL22432024 0.79 NOTUM (0.39) MAPK1SMN1; SMN2CASP3SENP8SENP7
SCHEMBL8679025 0.78 DPP4 (0.35) MAPK1SMN1; SMN2PTGS2DPP4PDCD1
SCHEMBL31510648 0.78 HNF4A (0.43) MAPK1SMN1; SMN2CASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3238749-B2 TISSUE PLUG 3 D MATRIX LTD (JP) 2025-06-04 EP claimed
US-20240115652-A1 TISSUE OCCLUDING AGENT COMPRISING AN IEIKIEIKIEIKI PEPTIDE 3 D MATRIX LTD (JP) 2024-04-11 US claimed
US-11801281-B2 Tissue occluding agent comprising an ieikieikieiki peptide 3-D MATRIX, LTD. (JP) 2023-10-31 US claimed
EP-4183425-A1 TISSUE PLUG 3-D Matrix Ltd. (JP) 2023-05-24 EP claimed
EP-3800197-B1 TISSUE PLUG 3 D MATRIX LTD (JP) 2022-09-28 EP claimed
US-20220193184-A1 TISSUE OCCLUDING AGENT COMPRISING AN IEIKIEIKIEIKI PEPTIDE 3-D MATRIX, LTD. (JP) 2022-06-23 US claimed
EP-3800197-A1 TISSUE PLUG 3-D Matrix Ltd. (JP) 2021-04-07 EP claimed
EP-3470093-B1 TISSUE PLUG 3 D MATRIX LTD (JP) 2020-08-19 EP claimed
US-20200222496-A1 TISSUE OCCLUDING AGENT 3-D MATRIX, LTD. (JP) 2020-07-16 US claimed
US-10596225-B2 Tissue occluding agent comprising an IEIKIEIKIEIKI peptide 3-D MATRIX, LTD. (JP) 2020-03-24 US claimed
EP-3470093-A1 TISSUE PLUG 3-D Matrix Ltd. (JP) 2019-04-17 EP claimed
EP-3238749-B1 TISSUE PLUG 3 D MATRIX LTD (JP) 2018-09-19 EP claimed
EP-3238749-A1 TISSUE PLUG 3-D Matrix Ltd. (JP) 2017-11-01 EP claimed
US-20140336144-A1 External Preparation Containing NSAIDS And Method For Producing The External Preparation NEXT21 K.K. (JP) 2014-11-13 US claimed
US-20140038909-A1 TISSUE OCCLUDING AGENT 3-D MATRIX, LTD. (JP) 2014-02-06 US claimed
US-20120183600-A1 NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS CHEN CHIEN-HUNG (US) 2012-07-19 US claimed
US-20120135955-A1 External Preparation Containing NSAIDs And Method For Producing The External Preparation THE UNIVERSITY OF TOKYO (JP) 2012-05-31 US claimed
EP-2457566-A1 EXTERNAL PREPARATION CONTAINING NSAIDs AND METHOD FOR PRODUCING THE EXTERNAL PREPARATION Next 21 K.K. (JP) 2012-05-30 EP claimed
US-20110201541-A1 TISSUE OCCLUDING AGENT 3-D MATRIX, LTD. (JP) 2011-08-18 US claimed
EP-2345433-A1 TISSUE PLUG 3-D Matrix, Ltd. (JP) 2011-07-20 EP claimed