Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13918749 | 0.90 | KDM4E (0.70) | KDM4EKMT2ANAMPTL3MBTL1ALDH1A1 | |
| SCHEMBL2967223 | 0.89 | L3MBTL1 (0.63) | KDM4EKMT2AL3MBTL1EPHX2ALDH1A1 | |
| SCHEMBL15168443 | 0.88 | LMNA (0.55) | KDM4EKMT2AEPHX2NR1H4ALDH1A1 | |
| SCHEMBL5072880 | 0.87 | L3MBTL1 (0.71) | KDM4EKMT2AL3MBTL1ALDH1A1NAAA | |
| SCHEMBL28758082 | 0.86 | L3MBTL1 (0.73) | KMT2AL3MBTL1ALDH1A1NAAAMAPK1 | |
| SCHEMBL19455890 | 0.86 | L3MBTL1 (0.73) | KMT2AL3MBTL1ALDH1A1NAAAMAPK1 | |
| SCHEMBL28327476 | 0.86 | L3MBTL1 (0.73) | KMT2AL3MBTL1ALDH1A1NAAAMAPK1 | |
| SCHEMBL11220824 | 0.86 | L3MBTL1 (0.73) | KMT2AL3MBTL1ALDH1A1NAAAMAPK1 | |
| SCHEMBL11224030 | 0.86 | L3MBTL1 (0.73) | KMT2AL3MBTL1ALDH1A1NAAAMAPK1 | |
| SCHEMBL27699888 | 0.86 | L3MBTL1 (0.73) | KMT2AL3MBTL1ALDH1A1NAAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864119-A1 | LIQUID COMPOSITION WITH DIHYDROXYTEREPHTHALIC ACID DIAMIDE COMPOUND WITH A HIGH SURFACTANT QUANTITY | Henkel AG & Co. KGaA (DE) | 2021-08-18 | — | — | EP | disclosed |
| US-7776847-B2 | Benzisothiazoles useful for treating or preventing HCV infection | RIGEL PHARMACEUTICALS, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-20060229294-A1 | Benzisothiazoles useful for treating or preventing HCV infection | RIGEL PHARMACEUTICALS, INC. (US) | 2006-10-12 | — | — | US | disclosed |
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229294-A1 | Benzisothiazoles useful for treating or preventing HCV infection | HAVCR2, ZC3HAV1, MAVS | KDM4E 2196/4885KMT2A 2900/4885NAMPT 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.